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Anti-Human Desmoglein-1 (Clone 129204) - 25 µg

Anti-Human Desmoglein-1 (Clone 129204) - 25 µg

ArtNr	LEIN-D355-25ug
Hersteller	Leinco Technologies
Menge	25 ug
Quantity options	25 ug 500 ug
Kategorie	Antibodies Western Blot ELISA Immunocytochemistry Primary Antibodies Immunostaining Immunochemistry
Typ	Antibody Monoclonal
Applikationen	WB, ICC, ELISA
Clon	129204
Specific against	Human (Homo sapiens)
Host	Mouse
Citations	1. Berean, K. et al. (2008) Pathology. 40(6):611-6.
NCBI	1828
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Versandbedingung	Raumtemperatur
Lieferbar
Manufacturer - Applications	ELISA Indirect, ICC, WB
Manufacturer - Category	Primary Monoclonal Antibodies>Growth Factors and Cytokines
Manufacturer - Targets	Desmoglein-1
Country of Origin	USA
Shipping Temperature	Next Day Ambient
Storage Conditions	The lyophilized antibody can be stored desiccated at -20°C to -70°C for up to twelve months. The reconstituted antibody can be stored for at least four weeks at 2-8°C. For long-term storage of the reconstituted antibody, aseptically aliquot into working volumes and store at -20°C to -70°C in a manual defrost freezer. Avoid repeated freeze thaw cycles. No detectable loss of activity was observed after six months.
Product Description	Desmoglein 1, also known as DSG1, is a human gene. Desmosomes are cell-cell junctions between epithelial, myocardial and certain other cell types. Desmoglein 1 is a calcium-binding transmembrane glycoprotein component of desmosomes in vertebrate epithelial cells. Currently, three desmoglein subfamily members have been identified and all are members of the cadherin cell adhesion molecule superfamily. DGI expression may be a significant factor for invasion, metastasis, and prognosis of human esophageal cancer. 1
Background	Desmoglein 1, also known as DSG1, is a human gene. Desmosomes are cell-cell junctions between epithelial, myocardial and certain other cell types. Desmoglein 1 is a calcium-binding transmembrane glycoprotein component of desmosomes in vertebrate epithelial cells. Currently, three desmoglein subfamily members have been identified and all are members of the cadherin cell adhesion molecule superfamily. DGI expression may be a significant factor for invasion, metastasis, and prognosis of human esophageal cancer. ¹
Other Applications Reported In Literature	Immunocytochemistry: Suitable for use at concentration of 5-25 µg/mL.
PubMed	Desmoglein-1
Manufacturer - Specificity	Mouse Anti-Human Desmoglein-1 (DSG1) (Clone 129204) recognizes an epitope on Human DSG1. This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
RRID	AB_2829935
Formulation	This monoclonal antibody has been 0.2 µm filtered and lyophilized from modified Dulbecco's phosphate buffered saline (1X PBS) pH 7.2 - 7.4 containing 5.0% w/v trehalose with no calcium, magnesium or preservatives present.
Endotoxin Level	< 0.1 EU/µg as determined by the LAL method
Immunogen	NS0-Derived Recombinant Human Desmoglein-1 Extracellular Domain (Accession # Q02413)
Additional Information	Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change.
Keywords	Monoclonal Antibody, Desmoglein-1, CDHF4, DG1, DSG, 129204, DSG1, Human, Anti-Human Desmoglein-1, Cadherin family member 4, CDHF4, CDHF4PPKS1, desmoglein 1, Desmoglein1, Desmoglein-1, Desmosomal glycoprotein 1, DG1, DGI, DSG, DSG1, Pemphigus foliaceus antigen, SPPK1

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LEIN-D355-25ug-safety-datasheet.pdf