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Anti-Human Eotaxin-2 (Clone 61016) - 500 µg

Anti-Human Eotaxin-2 (Clone 61016) - 500 µg

ArtNr	LEIN-E139-500ug
Hersteller	Leinco Technologies
Menge	500 ug
Quantity options	100 ug 25 ug 500 ug
Kategorie	Antibodies Western Blot ELISA Primary Antibodies Immunostaining
Typ	Antibody Monoclonal
Applikationen	WB, ELISA
Clon	61016
Specific against	Human (Homo sapiens)
Host	Mouse
Citations	1. Baggiolini, M. et al. (1997) J. Exp. Med. 185: 2171
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Versandbedingung	Raumtemperatur
Lieferbar
Manufacturer - Applications	ELISA Cap, N, WB
Manufacturer - Category	Primary Monoclonal Antibodies>Growth Factors and Cytokines
Manufacturer - Targets	Eotaxin-2
Country of Origin	USA
Shipping Temperature	Next Day Ambient
Storage Conditions	The lyophilized antibody can be stored desiccated at -20°C to -70°C for up to twelve months. The reconstituted antibody can be stored for at least four weeks at 2-8°C. For long-term storage of the reconstituted antibody, aseptically aliquot into working volumes and store at -20°C to -70°C in a manual defrost freezer. Avoid repeated freeze thaw cycles. No detectable loss of activity was observed after six months.
Product Description	Eotaxin-2 is a CC chemokine that is a specific agonist for the chemokine receptor CCR3. It is produced by activated monocytes and T lymphocytes. Eotaxin-2 induces chemotaxis of eosinophils as well as basophils and the release of histamine and leukotriene C4 from basophils. Eotaxin-2 has the same efficacy as eotaxin, but is somewhat less potent.1 Additionally, Eotaxin-2 inhibits the proliferation of multipotential hematopoietic progenitor cells.
Background	Eotaxin-2 is a CC chemokine that is a specific agonist for the chemokine receptor CCR3. It is produced by activated monocytes and T lymphocytes. Eotaxin-2 induces chemotaxis of eosinophils as well as basophils and the release of histamine and leukotriene C4 from basophils. Eotaxin-2 has the same efficacy as eotaxin, but is somewhat less potent.¹ Additionally, Eotaxin-2 inhibits the proliferation of multipotential hematopoietic progenitor cells.
Other Applications Reported In Literature	Neutralization: This antibody is useful for neutralization of Human Eotaxin-2 bioactivity. The antibody dose required to neutralize 50% (ND₅₀) of the biological activity of Human Eotaxin-2 (at 100 ng/ml) is 0.2 - 0.8 µg/ml.
PubMed	Eotaxin-2
Manufacturer - Specificity	Mouse Anti-Human Eotaxin-2 recognizes Human Eotaxin-2. This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
RRID	AB_2829989
Formulation	This monoclonal antibody has been 0.2 µm filtered and lyophilized from modified Dulbecco's phosphate buffered saline (1X PBS) pH 7.2 - 7.4 containing 5.0% w/v trehalose with no calcium, magnesium or preservatives present.
Endotoxin Level	< 0.1 EU/µg as determined by the LAL method
Immunogen	E. coli-Derived Recombinant Human CCL24 (Accession # AAB51135)
Additional Information	Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change.
Keywords	Monoclonal Antibody, Eotaxin-2, CCL24, MPIF-2, CkB-6, SCYA24, 61016, Eotaxin-2, Human, Anti-Human Eotaxin-2, CCL24, chemokine (C-C motif) ligand 24, Ckb-6, Eosinophil chemotactic protein 2, Eotaxin-2, member 24, MPIF2, MPIF-2, MPIF2Myeloid progenitor inhibitory factor 2, MPIF-2Small-inducible cytokine A24, SCYA24CK-beta-6

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LEIN-E139-500ug-safety-datasheet.pdf