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Anti-Mouse E-Selectin (Clone 96403) - 25 µg

Anti-Mouse E-Selectin (Clone 96403) - 25 µg

ArtNr	LEIN-E255-25ug
Hersteller	Leinco Technologies
Menge	25 ug
Quantity options	25 ug 500 ug
Kategorie	Antibodies Western Blot Primary Antibodies
Typ	Antibody Monoclonal
Applikationen	WB
Clon	96403
Specific against	Mouse (Murine, Mus musculus)
Host	Rat
Citations	1. Milstone, D. et al. (2004) PNAS 101: 8005 2. Dimitroff, CJ. et al. (2007) Expert Opin Ther Targets. 11(11):1473-91. 3. Hirata, T. et al. (2005) J Immunol. 175: 8042 4. Vanitha, R. et al. (2003) Cancer Res. 63: 6387
NCBI	25544
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Versandbedingung	Raumtemperatur
Lieferbar
Manufacturer - Applications	Quality Tested by Leinco Western Blotting: To detect Mouse E-Selectin this monoclonal antibody can be used at a concentration of 1-2 µg/ml. This monoclonal antibody should be used in conjunction with compatible second-step reagents such as PN:R377 and a chromogenic substrate such as PN:T343. The detection limit for Mouse E-Selectin is 1 ng/lane under either reducing or non-reducing conditions. The sensitivity of detection may increase up to 50 fold when a chemiluminescent substrate is used.
Manufacturer - Category	Primary Monoclonal Antibodies>Growth Factors and Cytokines
Manufacturer - Targets	E-Selectin
Country of Origin	USA
Shipping Temperature	Next Day Ambient
Storage Conditions	The lyophilized antibody can be stored desiccated at -20°C to -70°C for up to twelve months. The reconstituted antibody can be stored for at least four weeks at 2-8°C. For long-term storage of the reconstituted antibody, aseptically aliquot into working volumes and store at -20°C to -70°C in a manual defrost freezer. Avoid repeated freeze thaw cycles. No detectable loss of activity was observed after six months.
Product Description	E-selectin, also known as CD62E is an inducible leukocyte adhesion glycoprotein specifically expressed by endothelial cells.1 E-selectin helps initiate recruitment of circulating leukocytes to cutaneous, bone and inflamed tissues.2 E-selectin is found in inflammatory skin lesions in psoriasis, contact dermatitis, and delayed- type hypersensitivity, in arthritic joints, and in heart and renal allografts undergoing rejection.3 E-selectin-targeting antibody drug conjugate has potential as a prostate cancer therapy.4
Background	E-selectin, also known as CD62E is an inducible leukocyte adhesion glycoprotein specifically expressed by endothelial cells.¹ E-selectin helps initiate recruitment of circulating leukocytes to cutaneous, bone and inflamed tissues.² E-selectin is found in inflammatory skin lesions in psoriasis, contact dermatitis, and delayed- type hypersensitivity, in arthritic joints, and in heart and renal allografts undergoing rejection.³ E-selectin-targeting antibody drug conjugate has potential as a prostate cancer therapy.⁴
PubMed	E-Selectin
Manufacturer - Specificity	Rat Anti-Mouse E-Selectin (Clone 96403) recognizes an epitope on Mouse E-Selectin. This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
RRID	AB_2830027
Formulation	This monoclonal antibody has been 0.2 µm filtered and lyophilized from modified Dulbecco's phosphate buffered saline (1X PBS) pH 7.2 - 7.3 containing 5.0% w/v trehalose with no calcium, magnesium or preservatives present.
Endotoxin Level	< 0.1 EU/µg as determined by the LAL method
Immunogen	NS0-Derived Recombinant Mouse E-Selectin Extracellular Domain
Additional Information	Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change.
Keywords	Monoclonal Antibody, E-Selectin, SELE, CD62E, Endothelial Leukocyte Adhesion Molecule (ELAM), ELAM1, ESEL, LECAM2, 96403, Mouse, Anti-Mouse E-Selectin, CD62 antigen-like family member E, CD62E antigen, CD62E, ELAM, ELAM1, ELAM-1, ELAM1E-selectin, endothelial adhesion molecule 1, Endothelial leukocyte adhesion molecule 1, ESEL, E-Selectin, LECAM2, leukocyte endothelial cell adhesion molecule 2, Leukocyte-endothelial cell adhesion molecule 2, SELE, selectin E

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LEIN-E255-25ug-safety-datasheet.pdf