Anti-Mouse Flt-3 Ligand - 100 µg

ELISA Cap, ICC, N, WB

Flt-3 Ligand

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Fms-related tyrosine kinase 3 ligand (FLT3LG) is a hematopoietic four helical bundle cytokine. It is structurally homologous to stem cell factor (SCF) and colony stimulating factor 1 (CSF-1). In synergy with other growth factors, such as IL-7 and IL-3, Flt-3 ligand promotes long-term expansion and differentiation of human pro-B-cells.1, 2 Flt3 ligand is a cytokine capable of inducing large numbers of dendritic cells that dramatically enhances the sensitivity of antigen-specific B and T cell responses to systemic injection of a soluble protein. Through a CD40-CD40 ligand-dependent mechanism Flt-3 Ligand influences the class of antibody produced and enables productive immune responses.3

Neutralization: This antibody is useful for neutralization of Mouse Flt-3 Ligand bioactivity. The antibody dose required to neutralize 50% (ND₅₀) of the biological activity of Mouse Flt-3 Ligand (at 10 ng/ml) is 0.05-0.25 µg/ml.
Immunocytochemistry: Suitable for use at concentration of5-15 µg/mL.

Goat Anti-Mouse Flt-3 Ligand recognizes Mouse Flt-3 Ligand. This antigen affinity purified polyclonal antibody was purified using a proprietary chromatographic technique that includes covalently immobilizing the antigen proteins or peptides to agarose based beads. This purification method enhances specificity, reduces nonspecific binding of extraneous IgG and provides you with the most reliable reagent available for your early discovery research.

This antigen affinity purified polyclonal antibody has been 0.2 µm filtered and lyophilized from modified Dulbecco’s phosphate buffered saline (1X PBS) pH 7.2 – 7.3 containing 5.0% w/v trehalose with no calcium, magnesium, or preservatives present.

Purified Recombinant Mouse Flt-3 Ligand (> 98%)

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