Anti-Human FGF-16 - 100 µg

ICC, IHC, N, WB

FGF-16

Next Day Ambient

Fibroblast growth factor 16 (FGF16) is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. FGF16 has been reported as the sixteenth member of the heparin sulphate proteoglycan binding growth factor family, which includes acidic and basic FGFs (FGF-1 and FGF-2), based on sequence similarity.1 FGF-16 is most similar to FGF-9. FGF-16 is released from neonatal cardiac myocytes and alters growth-related signaling, possibly interfering with cardiac myocyte proliferative potential.2

Neutralization: This antibody is useful for neutralization of Human FGF-16 bioactivity. The antibody dose required to neutralize 50% (ND₅₀) of the biological activity of Human FGF-16 (at 100 ng/ml) is 3 - 9 µg/ml.
Immunohistochemistry: Suitable for use at concentration of 3-15 µg/mL.
Immunocytochemistry: Suitable for use at concentration of 5-15 µg/mL.

Goat Anti-Human Fibroblast Growth Factor-16 (FGF-16) recognizes Human FGF-16. This antigen affinity purified polyclonal antibody was purified using a proprietary chromatographic technique that includes covalently immobilizing the antigen proteins or peptides to agarose based beads. This purification method enhances specificity, reduces nonspecific binding of extraneous IgG and provides you with the most reliable reagent available for your early discovery research.

This antigen affinity purified polyclonal antibody has been 0.2 µm filtered and lyophilized from modified Dulbecco’s phosphate buffered saline (1X PBS) pH 7.2 – 7.3 containing 5.0% w/v trehalose with no calcium, magnesium, or preservatives present.

Purified Recombinant Human FGF-16 (> 98%)

Polyclonal Antibody, Fibroblast Growth Factor-16, FGFG, FGF-16, Human FGF-16, Anti-Human FGF-16, FGF16, FGF-16, fibroblast growth factor 16