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Anti-Human GFRα-2 (Intermediate Domain) - 0.1 mg

ArtNr LEIN-G577-0.1mg
Hersteller Leinco Technologies
Menge 0.1 mg
Quantity options 0.1 mg 20 ug
Kategorie
Typ Antibody Primary
Applikationen WB, IHC
Specific against Human (Homo sapiens)
Host Rabbit
Citations 1. Lewin GR et al. (2002) J Physiol. 545: 43
2. Mulligan Lois M et al. (2001) Human Genetics 108: 409
3. Herzig KH et al. (2005) Diabetes 54: 1324
NCBI 2675
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Versandbedingung Raumtemperatur
Lieferbar
Manufacturer - Applications
IHC FFPE, WB
Manufacturer - Category
Polyclonal Antibodies>Neuroscience
Manufacturer - Targets
Glial Cell Line-Derived Neurotropic Factor soluble Receptor Alpha 2
Country of Origin
USA
Shipping Temperature
Next Day Ambient
Storage Conditions
This polyclonal antibody is stable for at least one week when stored at 2-8°C. For long term storage, aliquot in working volumes without diluting and store at –20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.
Product Description
Glial cell line-derived neurotrophic factor family receptor alpha-2, also known as GFRA2, is the cognate co-receptor for the neurotrophic factor neurturin that is selectively expressed by isolectin B(4) (IB 4)-binding nociceptive sensory neurons.1 GFRA2 is required for the development of the myenteric nerve plexus and is an excellent candidate gene for Hirschsprung disease (HSCR).2 GFRalpha2 signaling is also needed for development of the parasympathetic islet innervation that is critical for vagally induced hormone secretion.3
Background
Glial cell line-derived neurotrophic factor family receptor alpha-2, also known as GFRA2, is the cognate co-receptor for the neurotrophic factor neurturin that is selectively expressed by isolectin B(4) (IB 4)-binding nociceptive sensory neurons.1 GFRA2 is required for the development of the myenteric nerve plexus and is an excellent candidate gene for Hirschsprung disease (HSCR).2 GFRalpha2 signaling is also needed for development of the parasympathetic islet innervation that is critical for vagally induced hormone secretion.3
PubMed
Glial Cell Line-Derived Neurotropic Factor soluble Receptor Alpha 2
Manufacturer - Specificity
Rabbit Anti-Human GFRα-2 recognizes an epitope in the intermediate domain of Human, Mouse and Rat GFRα-2. This polyclonal antibody was purified using affinity chromatography.
RRID
AB_2830236
Concentration
0.5 mg/ml
Formulation
This polyclonal antibody is formulated in phosphate buffered saline (PBS) pH 7.4 containing 0.02% sodium azide as a preservative.
Immunogen
PN:G624
Additional Information
Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change.
Keywords
Polyclonal Antibody, Glial Cell-Line derived Neurotrophic Factor soluble Receptor Alpha 2, GDNFRB, NRTNR-Alpha, NTNRA, RETL2, TRNR2, GFRα-2, Human, Anti-Human GFRα-2 (Intermediate Domain)

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 0.1 mg
Lieferbar: In stock
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Lieferung vsl. bis 30.10.2025 

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