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Anti-Human HB-EGF (Clone 125923) - 100 µg

Anti-Human HB-EGF (Clone 125923) - 100 µg

ArtNr	LEIN-H1483-100ug
Hersteller	Leinco Technologies
Menge	100 ug
Quantity options	100 ug 25 ug 500 ug
Kategorie	Oncology Neuroscience Neural Signaling Antibodies By Cell Type Carcinoma Cell Biology Cell Culture Cytokines Western Blot Primary Antibodies
Typ	Antibody Monoclonal
Applikationen	WB
Clon	125923
Specific against	Human (Homo sapiens)
Host	Mouse
Citations	1. Higashiyama, S. et al. (1993) Journal of Cell Biology 122: 933 2. Higashiyama, S. et al. (2004) Cytokine Growth Factor Rev. 15: 13 3. Miyamoto, S. et al. (2008) Mol Cancer Ther. 7: 3441
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Versandbedingung	Raumtemperatur
Lieferbar
Manufacturer - Applications	Quality Tested by Leinco Western Blotting: To detect Human HB-EGF this monoclonal antibody can be used at a concentration of 1 µg/ml. This monoclonal antibody should be used in conjunction with compatible second-step reagents such as PN:M114 and a chromogenic substrate such as PN:T343. The detection limit for Human HB-EGF is 5 ng/lane under either reducing or non-reducing conditions. The sensitivity of detection may increase up to 50 fold when a chemiluminescent substrate is used. A suitable Western blotting control is PN:H1419.
Manufacturer - Category	Primary Monoclonal Antibodies>Growth Factors and Cytokines
Manufacturer - Targets	HB-EGF
Country of Origin	USA
Shipping Temperature	Next Day Ambient
Storage Conditions	The lyophilized antibody can be stored desiccated at -20°C to -70°C for up to twelve months. The reconstituted antibody can be stored for at least four weeks at 2-8°C. For long-term storage of the reconstituted antibody, aseptically aliquot into working volumes and store at -20°C to -70°C in a manual defrost freezer. Avoid repeated freeze thaw cycles. No detectable loss of activity was observed after six months.
Product Description	Heparin-binding EGF-like growth factor (HB-EGF) is a monomeric heparin binding O-glycosylated protein1 and a member of the EGF family of proteins. It has been shown to play a role in wound healing, cardiac hypertrophy and heart development and function.2 HB-EGF contributes to cell adhesion, invasion, and angiogenesis, which are integral to transcoelomic metastasis in ovarian cancer.3
Background	Heparin-binding EGF-like growth factor (HB-EGF) is a monomeric heparin binding O-glycosylated protein¹ and a member of the EGF family of proteins. It has been shown to play a role in wound healing, cardiac hypertrophy and heart development and function.² HB-EGF contributes to cell adhesion, invasion, and angiogenesis, which are integral to transcoelomic metastasis in ovarian cancer.³
PubMed	HB-EGF
Manufacturer - Specificity	Mouse Anti-Human Heparin-Binding EGF-Like Growth Factor (HB-EGF) (Clone 125923) recognizes an epitope on Human HB-EGF. This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype. This antibody shows no cross-reactivity with rhAR, rhBTC, rhHRG-α, rhHRG-β, rhEGF and rhTGF-α.
RRID	AB_2830319
Formulation	This monoclonal antibody has been 0.2 µm filtered and lyophilized from modified Dulbecco's phosphate buffered saline (1X PBS) pH 7.2 - 7.3 containing 5.0% w/v trehalose with no calcium, magnesium or preservatives present.
Endotoxin Level	< 0.1 EU/µg as determined by the LAL method
Immunogen	Purified Recombinant Human HB-EGF (Accession # Q53H93)
Additional Information	Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change.
Keywords	Monoclonal Antibody, Heparin-Binding EGF-Like Growth Factor, DTR, DTS, DTSF, HEGFL, 125923, HB-EGF, Human, Anti-Human HB-EGF, diphtheria toxin receptor (heparin-binding epidermal growth factor-like growthfactor), Dtr, DTRHEGFLdiphtheria toxin receptor (heparin-binding EGF-like growth factor), Dts, DTSF, HBEGF, HB-EGF, Hegfl, heparin-binding EGF-like growth factor, heparin-binding epidermal growth factor, proheparin-binding EGF-like growth factor

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LEIN-H1483-100ug-safety-datasheet.pdf