Anti-Mouse IFNAR-1 [Clone MAR1-5A3] — APC - 100 µg

Quality Tested by Leinco FC The suggested concentration for clone MAR1-5A3 APC conjugated antibody for staining cells in flow cytometry is ≤ 1.0 μg per 10⁶ cells in a volume of 100 μl or 100μl of whole blood. Titration of the reagent is recommended for optimal performance for each application.

IFNAR1

Next Day 2 - 8°C

IFNAR1 is a type I membrane protein, that in conjunction with IFNAR2, makes up the heterodimeric receptor that binds all type I IFNs, which includes IFN α and β. Binding and activation of the receptor stimulates Janus protein kinases, which leads to the phosphorylation of several other proteins, namely STAT1 and STAT2. IFNAR1 has also been shown to interact with PRMT1 and Tyrosine kinase 2. Type I IFNs are a family of cytokines that have been shown to promote anti-viral, anti-microbial, anti-tumor and autoimmune responses In vivo.

IFNAR1

IFN-α/β

AB_2830367

This Allophycocyanin (APC) conjugate is formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.4, 1% BSA and 0.09% sodium azide as a preservative.

This antibody was produced by In vivo genetic immunization of IFNAR1 knockout mice with a plasmid encoding the extracellular domain of murine IFNAR1.

Monoclonal Antibody, Interferon Alpha/Beta Receptor 1, CD118, Ifar, Ifnar, Ifrc, INF-a receptor, Interferon-α/β receptor α chain precursor, MAR1-5A3, IFNAR1, Mouse IFNAR1, Anti-Mouse Interferon α/β Receptor 1 (IFNAR1/CD118) - APC