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Anti-Mouse IL-4 [Clone BVD6-24G2] – Biotin - 50 µg

Anti-Mouse IL-4 [Clone BVD6-24G2] – Biotin - 50 µg

ArtNr	LEIN-I-1109-50ug
Hersteller	Leinco Technologies
Menge	50 ug
Quantity options	500 ug 50 ug
Kategorie	Antibodies ELISA Primary Antibodies Immunostaining
Typ	Antibody Monoclonal
Applikationen	ELISA
Clon	BVD6-24G2
Specific against	Mouse (Murine, Mus musculus)
Host	Rat
NCBI	16189
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Versandbedingung	Gekühlt
Lieferbar
Manufacturer - Applications	ELISA, ELISA Det, ELISPOT Det
Manufacturer - Category	Primary Monoclonal Antibodies>Growth Factors and Cytokines
Manufacturer - Targets	IL-4
Country of Origin	USA
Shipping Temperature	Next Day 2 - 8°C
Storage Conditions	This Biotin conjugate is stable when stored at 2-8°C. Do not freeze.
Product Description	IL-4 is a 15-19 kD pleiotropic immune cytokine secreted by activated TH2 cells. It has many biological roles, including the regulation in humoral and adaptive immunity, the inhibition of bone resorption, the stimulation of activated B-cell and T-cell proliferation, and initiation of allergic responses. Moreover, IL-4 induces a positive feedback loop by stimulating differentiation of naive helper T cells, or Th0 cells, to Th2 cells which in turn secrete more IL-4. Increased IL-4 production and overproduction of IL-4R are found in many cancers. IL-4 has a significant effect on tumor progression by increasing apoptosis resistance via tumor growth enhancement. IL-4 may also play a part in the immune dysregulation that occurs in most HIV-1 infected patients.
Background	IL-4 is a 15-19 kD pleiotropic immune cytokine secreted by activated TH2 cells. It has many biological roles, including the regulation in humoral and adaptive immunity, the inhibition of bone resorption, the stimulation of activated B-cell and T-cell proliferation, and initiation of allergic responses. Moreover, IL-4 induces a positive feedback loop by stimulating differentiation of naive helper T cells, or Th0 cells, to Th2 cells which in turn secrete more IL-4. Increased IL-4 production and overproduction of IL-4R are found in many cancers. IL-4 has a significant effect on tumor progression by increasing apoptosis resistance via tumor growth enhancement. IL-4 may also play a part in the immune dysregulation that occurs in most HIV-1 infected patients.
PubMed	IL-4
Manufacturer - Research Area	Cell Biology, Stem Cell, Other Molecules
Manufacturer - Specificity	Clone BVD6-24G2 recognizes an epitope on mouse IL-4.
RRID	AB_2830444
Concentration	0.5 mg/ml
Formulation	This biotinylated antibody is formulated in 0.01 M phosphate buffered saline (PBS) pH 7.4, 150 mM NaCl, 1% BSA and 0.09% sodium azide as a preservative.
Immunogen	Purified Recombinant Mouse IL-4 (> 98%)
Additional Information	Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change.
Keywords	Monoclonal Antibody, Interleukin-4, BCGF, BCDF, B Cell Stimulating Factor, BSF-1, IaIF, HCGF, MCGF2, MFF, TCGF-2, BVD6-24G2, IL-4, Mouse, Anti-Mouse IL-4 - Biotin

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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LEIN-I-1109-50ug-safety-datasheet.pdf