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Anti-Mouse IFNγ [Clone XMG1.2] — Biotin - 50 µg

ArtNr LEIN-I-1121-50ug
Hersteller Leinco Technologies
Menge 50 ug
Quantity options 500 ug 50 ug
Kategorie
Typ Antibody Monoclonal
Applikationen ELISA
Clon XMG1.2
Specific against Mouse (Murine, Mus musculus)
Host Rat
Citations 1. Goeddel DV et al. (1982) Nature 298: 859
2. Wilson CB et al. (2007) Adv. Immunol. 96: 41
3. Hume DA et al. (2004) J Leukoc Biol. 75: 163
4. Teijaro et al. (2020) bioRxiv 22: 24
5. Feldmann et al. (2021) Microorganisms 9(2): 279
NCBI 15978
ECLASS 10.1 42030590
ECLASS 11.0 42030590
UNSPSC 12352203
Versandbedingung Gekühlt
Lieferbar
Manufacturer - Applications
ELISA Det, ELISPOT Det, ICFC
Manufacturer - Category
Primary Monoclonal Antibodies>Growth Factors and Cytokines
Manufacturer - Targets
IFNγ
Country of Origin
USA
Shipping Temperature
Next Day 2 - 8°C
Storage Conditions
This Biotin conjugate is stable when stored at 2-8°C. Do not freeze.This biotinylated antibody is stable when stored at 2-8°C. Do not freeze.
Product Description
Interferon-gamma (IFN-γ) or type II interferon is a dimerized soluble cytokine that is the only member of the type II class of interferons.1 It is a cytokine critical for innate and adaptive immunity against viral and intracellular bacterial infections and for tumor control. IFNG is produced predominantly by natural killer (NK) and natural killer T (NKT) cells as part of the innate immune response, and by CD4 and CD8 cytotoxic T lymphocyte (CTL) effector T cells once antigen-specific immunity develops.2 IFN-γ has antiviral, immunoregulatory, and anti-tumour properties.3
Background
Interferon-gamma (IFN-γ) or type II interferon is a dimerized soluble cytokine that is the only member of the type II class of interferons.1 It is a cytokine critical for innate and adaptive immunity against viral and intracellular bacterial infections and for tumor control. IFNG is produced predominantly by natural killer (NK) and natural killer T (NKT) cells as part of the innate immune response, and by CD4 and CD8 cytotoxic T lymphocyte (CTL) effector T cells once antigen-specific immunity develops.2 IFN-γ has antiviral, immunoregulatory, and anti-tumour properties.3
Other Applications Reported In Literature
ICFC The suggested concentration for clone XMG1.2 Biotin conjugated antibody for staining cells in Intracellular Immunofluorescent flow cytometry is ≤ 1.0 μg per 106 cells in a volume of 100 μl or 100μl of whole blood. Titration of the reagent is recommended for optimal performance for each application.
ELISPOT Det
PubMed
IFN-γ
Manufacturer - Research Area
Other Molecules
Manufacturer - Specificity
Rat Anti-Mouse Interferon Gamma (IFN-γ) (Clone XMG1.2) recognizes an epitope on Mouse IFN-γ. This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
RRID
AB_2830457
Concentration
0.5 mg/ml
Formulation
This biotinylated antibody is formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.4, 1% BSA and 0.09% sodium azide as a preservative.
Immunogen
Purified Recombinant Mouse IFN-γ (> 98%)
Additional Information
Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change.
Keywords
Monoclonal Antibody, Interferon Gamma, Immune Interferon, Type II Interferon, T Cell Interferon, MAF, IFNG, IFG, IFI, XMG1.2, IFN-γ, Mouse, Anti-Mouse IFN-γ - Biotin

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 50 ug
Lieferbar: In stock
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