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Anti-Mouse IFN-gamma - Purified Functional Grade

Anti-Mouse IFN-gamma - Purified Functional Grade

ArtNr	LEIN-I-1130-100ug
Hersteller	Leinco Technologies
Menge	100 ug
Quantity options	1 mg 100 ug 25 mg 500 ug 5 mg
Kategorie	Antibodies Primary Antibodies
Typ	Antibody Primary
Applikationen	IHC, ELISA
Clon	R4-6A2
Specific against	Mouse (Murine, Mus musculus)
Host	Rat
Purity	>95% by SDS-PAGE and HPLC
Citations	1. Goeddel DV et al. (1982) Nature 298: 859 2. Wilson CB et al. (2007) Adv. Immunol. 96: 41 3. Hume DA et al. (2004) J Leukoc Biol. 75: 163
NCBI	15978
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Versandbedingung	Gekühlt
Lieferbar
Manufacturer - Applications	Quality Tested by Leinco ELISA Cap R4-6A2 antibody is useful as a detection antibody for a sandwich ELISA with a concentration range of 0.5-2.0 µg/ml as recommended.
Manufacturer - Category	Purified in vivo Functional Grade>Gold Purified Bulk Antibodies\|Primary Monoclonal Antibodies>Growth Factors and Cytokines
Manufacturer - Targets	IFN-γ
Country of Origin	USA
Shipping Temperature	Next Day 2-8°C
Storage Conditions	Functional grade preclinical antibodies may be stored sterile as received at 2-8°C for up to one month. For longer term storage, aseptically aliquot in working volumes without diluting and store at -80°C. Avoid Repeated Freeze Thaw Cycles.
Product Description	Interferon-gamma (IFN-γ) or type II interferon is a dimerized soluble cytokine that is the only member of the type II class of interferons.1 It is a cytokine critical for innate and adaptive immunity against viral and intracellular bacterial infections and for tumor control. IFNG is produced predominantly by natural killer (NK) and natural killer T (NKT) cells as part of the innate immune response, and by CD4 and CD8 cytotoxic T lymphocyte (CTL) effector T cells once antigen-specific immunity develops.2 IFN-γ has antiviral, immunoregulatory, and anti-tumour properties.3
Background	Interferon-gamma (IFN-γ) or type II interferon is a dimerized soluble cytokine that is the only member of the type II class of interferons.¹ It is a cytokine critical for innate and adaptive immunity against viral and intracellular bacterial infections and for tumor control. IFNG is produced predominantly by natural killer (NK) and natural killer T (NKT) cells as part of the innate immune response, and by CD4 and CD8 cytotoxic T lymphocyte (CTL) effector T cells once antigen-specific immunity develops.² IFN-γ has antiviral, immunoregulatory, and anti-tumour properties.³
Additional Reported Applications For Relevant Conjugates	IHC FF For specific conjugates of this clone, review literature for suggested application details.
Other Applications Reported In Literature	ELISPOT Cap ELISPOT Det N
PubMed	IFN-γ
Manufacturer - Specificity	Rat Anti-Mouse Interferon Gamma (IFN-γ) (Clone R4-6A2) recognizes an epitope on Mouse IFN-γ. This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
RRID	AB_2830468
Concentration	1.0 mg/ml
Formulation	This monoclonal antibody is aseptically packaged and formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.2 - 7.4 with no carrier protein, potassium, calcium or preservatives added. Due to inherent biochemical properties of antibodies, certain products may be prone to precipitation over time. Precipitation may be removed by aseptic centrifugation and/or filtration.
Endotoxin Level	< 0.5 EU/mg as determined by the LAL method
Immunogen	Purified Mouse IFN-γ
Additional Information	Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change.

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LEIN-I-1130-100ug-safety-datasheet.pdf