Anti-Mouse IFNAR-1 [Clone MAR1-5A3] — Purified - 200 µg

B, ELISA, FC, IP, WB

IFNAR1

Next Day 2 - 8°C

IFNAR1 is a type I membrane protein, that in conjunction with IFNAR2, makes up the heterodimeric receptor that binds all type I IFNs, which includes IFN α and β. Binding and activation of the receptor stimulates Janus protein kinases, which leads to the phosphorylation of several other proteins, namely STAT1 and STAT2. IFNAR1 has also been shown to interact with PRMT1 and Tyrosine kinase 2. Type I IFNs are a family of cytokines that have been shown to promote anti-viral, anti-microbial, anti-tumor and autoimmune responses In vivo.

WB
IP
B
ELISA

IFN-α/β

AB_2830666

This purified antibody is formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.4, 1% BSA and 0.09% sodium azide as a preservative.

This antibody was produced by In vivo genetic immunization of IFNAR1 knockout mice with a plasmid encoding the extracellular domain of murine IFNAR1.

Monoclonal Antibody, Interferon Alpha/Beta Receptor 1, CD118, Ifar, Ifnar, Ifrc, INF-a receptor, Interferon-α/β receptor α chain precursor , MAR1-5A3, IFNAR1, Mouse IFNAR1, Anti-Mouse Interferon α/β Receptor 1, MAR15a3