Anti-Mouse IL-1R (CD121a) [Clone JAMA-147] — PE - 500 µg

Quality Tested by Leinco Flow Cytometry The suggested use of this antibody is ≤1.0 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.

Interleukin-1 R1

Next Day 2 - 8°C

IL-1 binds two receptors, IL-1RI and IL-1RII. The ligands IL-1α and IL-1ß exert all of their various biological actions by binding IL-1RI. IL-1RII has a shortened cytoplasmic domain that is unable to transduce signals and therefore acts as a decoy receptor and competitively antagonizes the binding of IL-1α and IL-1ß, thereby reducing their biological effects. Binding of the ligands to IL-1RI is enhanced by an accessory protein, IL-1R-AcP. IL-1RI is expressed on T cells, thymocytes, dendritic cells, fibroblasts, vascular endothelial cells, epithelial cells and neural cells. It is an 80 kD transmembrane glycoprotein.

Innate and adaptive immune response

Blue Laser (488 nm) and/or Green Laser (532 nm)/Yellow-Green Laser (561 nm)

Armenian Hamster Anti-Mouse IL-1 R1 (Clone JAMA-147) recognizes Mouse IL-1 R1. This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.

0.2 mg/ml

This monoclonal antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions.

Extracellular domain of mouse IL-1R1

Monoclonal Antibody, Interleukin-1 R1, Interleukin-1 R1, JAMA-147, IL-1 R1, Mouse, Anti-Mouse IL-1 R1, Type 1-R-Phycoerythrin