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Anti-Human CD119 (IFN-γ Rα Chain)-PE - 50 µg

ArtNr LEIN-I-441-50ug
Hersteller Leinco Technologies
Menge 50 ug
Quantity options 500 ug 50 ug
Kategorie
Typ Antibody Monoclonal
Applikationen FC
Clon GIR-208
Specific against Human (Homo sapiens)
Host Mouse
ECLASS 10.1 42030590
ECLASS 11.0 42030590
UNSPSC 12352203
Versandbedingung Gekühlt
Lieferbar
Manufacturer - Applications
Quality Tested by Leinco FC The suggested concentration for clone GIR-208 PE conjugated antibody for staining cells in flow cytometry is ≤ .25 μg per 106 cells in a volume of 100 μl or 100μl of whole blood. Titration of the reagent is recommended for optimal performance for each application.
Manufacturer - Category
Primary Monoclonal Antibodies>Growth Factors and Cytokines
Manufacturer - Targets
IFNγ Rα
Country of Origin
USA
Shipping Temperature
Next Day 2 - 8°C
Storage Conditions
This R-PE conjugate is stable when stored at 2-8°C. Do not freeze.
Product Description
IFNγ Rα, or IFNγ R1, is a 90-100 kD type I transmembrane protein that is structurally related to IL-10 receptor. IFNγ Receptor consists of α and ß chains and requires association of JAK1, JAK2 and Stat1 for IFN-γ signal transduction which induces tyrosine phosphorylation of IFN-γ Rα leading to the formation of a docking site on the activated receptor for Stat1, which specifically activates IFN-γ induced gene transcription.
Background
IFNγ Rα, or IFNγ R1, is a 90-100 kD type I transmembrane protein that is structurally related to IL-10 receptor. IFNγ Receptor consists of α and ß chains and requires association of JAK1, JAK2 and Stat1 for IFN-γ signal transduction which induces tyrosine phosphorylation of IFN-γ Rα leading to the formation of a docking site on the activated receptor for Stat1, which specifically activates IFN-γ induced gene transcription.
Additional Reported Applications For Relevant Conjugates
WB
IP
IHC
B
PubMed
IFNγ Rα
Excitation Laser
Blue Laser (488 nm) and/or Green Laser (532 nm)/Yellow-Green Laser (561 nm)
Manufacturer - Research Area
Immunology
Manufacturer - Specificity
Clone GIR-208 recognizes an epitope on human IFNγ Rα.
RRID
AB_2830690
Concentration
0.2 mg/ml
Formulation
This R-phycoerythrin (R-PE) conjugate is formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.4, 1% BSA and 0.09% sodium azide as a preservative.
Antigen Distribution
The IFN-γ receptor is expressed at moderate levels on virtually every cell with the exception of erythrocytes.
Additional Information
Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change.
Keywords
Monoclonal Antibody, IFNγ Rα, Inteferon Gamma R Alpha, GIR 208, IFNGR1, Human, Anti-Human Interferon Gamma (IFNγ) Rα Chain-R-Phycoerythrin

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 50 ug
Lieferbar: In stock
lieferbar

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