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Anti-Human CD119 (IFN-γ Rα Chain) - Purified - 25 µg

Anti-Human CD119 (IFN-γ Rα Chain) - Purified - 25 µg

ArtNr	LEIN-I-442-25ug
Hersteller	Leinco Technologies
Menge	25 ug
Quantity options	100 ug 25 ug
Kategorie	Antibodies Flow Cytometry Primary Antibodies Functional Assays
Typ	Antibody Monoclonal
Applikationen	FC, FA
Clon	GIR-208
Specific against	Human (Homo sapiens)
Host	Mouse
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Versandbedingung	Raumtemperatur
Lieferbar
Manufacturer - Applications	Quality Tested by Leinco FC The suggested concentration for clone GIR-208 purified antibody for staining cells in flow cytometry is ≤ 0.5 μg per 10⁶ cells in a volume of 100 μl or 100μl of whole blood. Titration of the reagent is recommended for optimal performance for each application.
Manufacturer - Category	Primary Monoclonal Antibodies>Apoptosis & Cell Biology
Manufacturer - Targets	IFNγ Rα
Shipping Temperature	Next Day Ambient
Storage Conditions	This purified antibody is stable when stored at 2-8°C. Do not freeze.
Product Description	IFNγ Rα, or IFNγ R1, is a 90-100 kD type I transmembrane protein that is structurally related to IL-10 receptor. IFNγ Receptor consists of α and ß chains and requires association of JAK1, JAK2 and Stat1 for IFN-γ signal transduction which induces tyrosine phosphorylation of IFN-γ Rα leading to the formation of a docking site on the activated receptor for Stat1, which specifically activates IFN-γ induced gene transcription.
Background	IFNγ Rα, or IFNγ R1, is a 90-100 kD type I transmembrane protein that is structurally related to IL-10 receptor. IFNγ Receptor consists of α and ß chains and requires association of JAK1, JAK2 and Stat1 for IFN-γ signal transduction which induces tyrosine phosphorylation of IFN-γ Rα leading to the formation of a docking site on the activated receptor for Stat1, which specifically activates IFN-γ induced gene transcription.
Additional Reported Applications For Relevant Conjugates	WB IP IHC B
Other Applications Reported In Literature	FA The Purified antibody is recommended for functional assays. Clone GIR-208 can be used as an isotype with Clone MAR1-5A3 (Anti-Mouse IFNAR1)
PubMed	IFNγ Rα
Manufacturer - Research Area	Immunology
Manufacturer - Specificity	Clone GIR-208 recognizes an epitope on human IFNγ Rα.
RRID	AB_2830691
Concentration	0.5 mg/ml
Formulation	This purified antibody is formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.4, 1% BSA and 0.09% sodium azide as a preservative.
Antigen Distribution	The IFN-γ receptor is expressed at moderate levels on virtually every cell with the exception of erythrocytes.
Additional Information	Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change.
Keywords	Monoclonal Antibody, IFNγ Rα, Interferon Gamma R Alpha Chain, CD119, GIR 208, IFNGR1, Human, Anti-Human IFN-γ Rα Chain - Purified

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LEIN-I-442-25ug-safety-datasheet.pdf