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Anti-Human IL-13 Rα1 - 25 µg

Anti-Human IL-13 Rα1 - 25 µg

ArtNr	LEIN-I-625-25ug
Hersteller	Leinco Technologies
Menge	25 ug
Quantity options	25 ug 500 ug
Kategorie	Antibodies Western Blot ELISA Primary Antibodies Immunostaining
Typ	Antibody Monoclonal
Applikationen	WB, ELISA
Clon	116730
Specific against	Human (Homo sapiens)
Host	Mouse
Citations	1. Caput, D. et al. (1996) J. Biol. Chem. 271:16921 2. Donaldson, DD. et al. (1998) J. Immunol. 161:2317 3. Hilton, DJ. et al. (1996) Proc. Natl. Acad. Sci. (USA) 93:497 4. Zhang, JG. et al. (1997) J. Biol. Chem. 272:9474 5. Orchansky, PL. et al. (1999) J. Biol. Chem. 274:0818
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Versandbedingung	Raumtemperatur
Lieferbar
Manufacturer - Applications	ELISA Cap, WB
Manufacturer - Category	Primary Monoclonal Antibodies>Growth Factors and Cytokines
Manufacturer - Targets	IL-13 R alpha 1
Country of Origin	USA
Shipping Temperature	Next Day Ambient
Storage Conditions	The lyophilized antibody can be stored desiccated at -20°C to -70°C for up to twelve months. The reconstituted antibody can be stored for at least four weeks at 2-8°C. For long-term storage of the reconstituted antibody, aseptically aliquot into working volumes and store at -20°C to -70°C in a manual defrost freezer. Avoid repeated freeze thaw cycles. No detectable loss of activity was observed after six months.
Product Description	Interleukin 13 receptor, alpha 1, also known as IL13RA1 and CD213A1 (cluster of differentiation 213A1) is a subunit of the interleukin 13 receptor. This subunit forms a receptor complex with IL4 receptor alpha, a subunit shared by IL13 and IL4 receptors. This subunit serves as a primary IL13-binding subunit of the IL13 receptor, and may also be a component of IL4 receptors. This protein has been shown to bind tyrosine kinase TYK2, and thus may mediate the signaling processes that lead to the activation of JAK1, STAT3 and STAT6 induced by IL13 and IL4. IL-13Ralpha1is essential for allergen-induced airway hyperreactivity and mucus hypersecretion.1
Background	Interleukin 13 receptor, alpha 1, also known as IL13RA1 and CD213A1 (cluster of differentiation 213A1) is a subunit of the interleukin 13 receptor. This subunit forms a receptor complex with IL4 receptor alpha, a subunit shared by IL13 and IL4 receptors. This subunit serves as a primary IL13-binding subunit of the IL13 receptor, and may also be a component of IL4 receptors. This protein has been shown to bind tyrosine kinase TYK2, and thus may mediate the signaling processes that lead to the activation of JAK1, STAT3 and STAT6 induced by IL13 and IL4. IL-13Ralpha1is essential for allergen-induced airway hyperreactivity and mucus hypersecretion.¹
PubMed	IL-13 R alpha 1
Manufacturer - Specificity	Mouse Anti-Human IL-13 Receptor α1 (IL-13 Rα1) (Clone 116730) recognizes an epitope on Human IL-13 Rα1. This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype. No cross-reactivity was observed with rmIL-13 Rα1, rhIL-13 Rα2, rhIL-4 R, rhIL-5 Rα, rhIL-5 Rβ, or rhIL-9 R
RRID	AB_2830747
Formulation	This monoclonal antibody has been 0.2 µm filtered and lyophilized from modified Dulbecco's phosphate buffered saline (1X PBS) pH 7.2 - 7.3 containing 5.0% w/v trehalose with no calcium, magnesium or preservatives present.
Immunogen	Purified Recombinant Human IL-13 Rα1 (Accession # P78552)
Additional Information	Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change.
Keywords	Monoclonal Antibody, Interleukin-13 Receptor Alpha 1, IL13RA1, CD213A1, IL-13Ra, NR4, 116730, IL-13 Rα1, Human, Anti-Human IL-13 Rα1, bB128O4.2.1 (interleukin 13 receptor, alpha 1), Cancer/testis antigen 19, CD213a1 antigen, CD213a1, CT19, IL-13 R alpha 1, IL13 receptor alpha-1 chain, IL-13 receptor subunit alpha-1, IL13R alpha 1, IL-13R subunit alpha-1, IL13R, IL13RA, IL-13Ra, IL13RA1, IL-13Ra1, IL-13R-alpha-1, interleukin 13 receptor, alpha 1, interleukin-13 receptor subunit alpha-1, NR4

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LEIN-I-625-25ug-safety-datasheet.pdf