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Anti-Human IL-17R - 100 µg

ArtNr LEIN-I-627-100ug
Hersteller Leinco Technologies
Menge 100 ug
Quantity options 100 ug 25 ug 500 ug
Kategorie
Typ Antibody Monoclonal
Applikationen WB, FC
Clon 133617
Specific against Human (Homo sapiens)
Host Mouse
Citations 1. Facchini, A. et al. (2007) J clin. Research clin. oncol. 133: 1017
2. Armitage, RJ. et al.(1997) Cytokine. 9(11):794-800.
ECLASS 10.1 42030590
ECLASS 11.0 42030590
UNSPSC 12352203
Versandbedingung Raumtemperatur
Lieferbar
Manufacturer - Applications
CyTOF®, FC, N, WB
Manufacturer - Category
Primary Monoclonal Antibodies>Growth Factors and Cytokines
Manufacturer - Targets
IL-17R
Country of Origin
USA
Shipping Temperature
Next Day Ambient
Storage Conditions
The lyophilized antibody can be stored desiccated at -20°C to -70°C for up to twelve months. The reconstituted antibody can be stored for at least four weeks at 2-8°C. For long-term storage of the reconstituted antibody, aseptically aliquot into working volumes and store at -20°C to -70°C in a manual defrost freezer. Avoid repeated freeze thaw cycles. No detectable loss of activity was observed after six months.
Product Description
Interleukin-17 receptor (IL-17R) Type 1 transmembrane glycoprotein which binds interleukin 17. IL-17R signaling is critical for pulmonary neutrophil recruitment and host defense against Gram-negative bacteria.1 It represents a marker for the metastasizing ability of osteosarcoma.1
Background
Interleukin-17 receptor (IL-17R) Type 1 transmembrane glycoprotein which binds interleukin 17. IL-17R signaling is critical for pulmonary neutrophil recruitment and host defense against Gram-negative bacteria.1 It represents a marker for the metastasizing ability of osteosarcoma.1
Other Applications Reported In Literature
Neutralization: At 2 μg/mL, this antibody will neutralize 70 - 90% of human IL-17 receptor-mediatedbioactivity in the presence of 25 ng/mL of rhIL-17 using IL-17-dependent secretion of IL-6by the NHDF cell line as an assay.
CyTOF-ready:Ready to be labeled using established conjugation methods. No BSA or other carrier proteins that could interfere with conjugation.
PubMed
IL-17R
Manufacturer - Specificity
Mouse Anti-Human Interleukin 17 Receptor (IL-17R) (Clone 133617) recognizes an epitope on Human IL-17R. This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
RRID
AB_2830749
Formulation
This monoclonal antibody has been 0.2 µm filtered and lyophilized from modified Dulbecco's phosphate buffered saline (1X PBS) pH 7.2 - 7.3 containing 5.0% w/v trehalose with no calcium, magnesium or preservatives present.
Immunogen
Purified Recombinant Human IL-17R (Accession # Q96F46)
Additional Information
Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change.
Keywords
Monoclonal Antibody, Interleukin-17 Receptor, IL17R, CDw217, IL-17RA, IL17RA, MGC10262, 133617, IL-17R, Human, Anti-Human IL-17R, CD217 antigen, CD217, Cdw217, CDw217interleukin 17 receptor, hIL-17R, IL-17 R, IL-17 RA, IL-17 receptor A, IL17RA, IL-17RA, IL-17RAMGC10262, IL17Rinterleukin-17 receptor A, interleukin 17 receptor A

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ug
Lieferbar: In stock
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