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Anti-Human IGFBP-2 - 25 µg

Anti-Human IGFBP-2 - 25 µg

ArtNr	LEIN-I-731-25ug
Hersteller	Leinco Technologies
Menge	25 ug
Quantity options	100 ug 25 ug
Kategorie	Antibodies Western Blot Primary Antibodies
Typ	Antibody Primary
Applikationen	WB
Specific against	Human (Homo sapiens)
Host	Caprine
Citations	1. Luthman, H. et al.(1991) Biochem Biophys Res Commun. 176: 1250 2. Disis, ML. et al.(2008) Cancer Res. 68: 8400
NCBI	3485
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Versandbedingung	Raumtemperatur
Lieferbar
Manufacturer - Applications	N, WB
Manufacturer - Category	Polyclonal Antibodies>Growth Factors & Cytokines
Manufacturer - Targets	IGFBP-2
Country of Origin	USA
Shipping Temperature	Next Day Ambient
Storage Conditions	The lyophilized antigen affinity purified polyclonal antibody can be stored desiccated at -20°C to -70°C for twelve months from date of receipt. The reconstituted antibody can be stored for at least four weeks at 2-8°C. For long-term storage of the reconstituted antibody, aseptically aliquot into working volumes and store at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. No detectable loss of activity was observed after six months.
Product Description	Insulin-like growth factor binding protein 2, also known as IGFBP2, is an extracellular unglycosylated polypeptide that specifically binds IGF and modulates its effects.1 IGFBP-2 has direct effects on breast cancer proliferation via stimulation of critical signaling pathways.2
Background	Insulin-like growth factor binding protein 2, also known as IGFBP2, is an extracellular unglycosylated polypeptide that specifically binds IGF and modulates its effects.¹ IGFBP-2 has direct effects on breast cancer proliferation via stimulation of critical signaling pathways.²
Other Applications Reported In Literature	Neutralization: This antibody is useful for neutralization of Human IGFBP-2 bioactivity. The antibody dose required to neutralize 50% (ND₅₀) of the biological activity of Human IGFBP-2 (at 14 ng/ml) is 2.5 - 7.5 µg/ml.
PubMed	IGFBP-2
Manufacturer - Specificity	Goat Anti-Human Insulin-Like Growth Factor Binding Protein 2 (IGFBP-2) recognizes Human IGFBP-2. This antigen affinity purified polyclonal antibody was purified using a proprietary chromatographic technique that includes covalently immobilizing the antigen proteins or peptides to agarose based beads. This purification method enhances specificity, reduces nonspecific binding of extraneous IgG and provides you with the most reliable reagent available for your early discovery research.
RRID	AB_2830852
Formulation	This antigen affinity purified polyclonal antibody has been 0.2 µm filtered and lyophilized from modified Dulbecco’s phosphate buffered saline (1X PBS) pH 7.2 – 7.3 containing 5.0% w/v trehalose with no calcium, magnesium, or preservatives present.
Endotoxin Level	< 0.1 EU/µg as determined by the LAL method
Immunogen	NS0-Derived Recombinant Human IGFBP-2
Additional Information	Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change.
Keywords	Polyclonal Antibody, Insulin-Like Growth Factor Binding Protein 2, IBP-2, IGF-BP53, IGFBP-2, Human IGFBP-2, Anti-Human IGFBP-2, BP2, IBP2, IBP-2, IGF-binding protein 2, IGFBP2, IGFBP-2, IGF-BP53, insulin-like growth factor binding protein 2 36kD, insulin-like growth factor binding protein 2, 36kDa, insulin-like growth factor-binding protein 2

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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LEIN-I-731-25ug-safety-datasheet.pdf