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Anti-Mouse IL-7 Rα - 100 µg

ArtNr LEIN-I-735-100ug
Hersteller Leinco Technologies
Menge 100 ug
Quantity options 100 ug 25 ug
Kategorie
Typ Antibody Primary
Applikationen WB, FC, ELISA
Specific against Mouse (Murine, Mus musculus)
Host Caprine
Citations 1. Fry, TJ. et al. (2005) J Immunol. 174: 6571
2. Murre, C. et al. (2002) Embo J. 21: 103
NCBI 16197
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Versandbedingung Raumtemperatur
Lieferbar
Manufacturer - Applications
ELISA Indirect, FC, WB
Manufacturer - Category
Polyclonal Antibodies>Growth Factors & Cytokines
Manufacturer - Targets
IL-7 Rα
Country of Origin
USA
Shipping Temperature
Next Day Ambient
Storage Conditions
The lyophilized antigen affinity purified polyclonal antibody can be stored desiccated at -20°C to -70°C for twelve months from date of receipt. The reconstituted antibody can be stored for at least four weeks at 2-8°C. For long-term storage of the reconstituted antibody, aseptically aliquot into working volumes and store at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. No detectable loss of activity was observed after six months.
Product Description
CD127 (IL7R-α) is a 60-90 kD type I cytokine receptor involved in the regulation of lymphopoiesis. The active receptor is an α/γ chain heterodimer. The common γ chain, which also associates with the IL-2 receptor, serves mainly to activate signal transduction via the IL7R complex. CD127 also interacts with the Thymic Stromal Lymphopoietin Receptor (TSLPR). CD127 determines signaling events via its association with cytoplasmic signaling molecules and has been reported to be a useful marker for identifying memory and effector T cells.
Background
CD127 (IL7R-α) is a 60-90 kD type I cytokine receptor involved in the regulation of lymphopoiesis. The active receptor is an α/γ chain heterodimer. The common γ chain, which also associates with the IL-2 receptor, serves mainly to activate signal transduction via the IL7R complex. CD127 also interacts with the Thymic Stromal Lymphopoietin Receptor (TSLPR). CD127 determines signaling events via its association with cytoplasmic signaling molecules and has been reported to be a useful marker for identifying memory and effector T cells.
Other Applications Reported In Literature
CyTOF-ready:Ready to be labeled using established conjugation methods. No BSA or other carrier proteins that could interfere with conjugation.
PubMed
IL-7 Rα
Manufacturer - Specificity
Goat Anti-Mouse Interleukin 7 Receptor Alpha (IL-7 Rα) recognizes Mouse IL-7 Rα. This antigen affinity purified polyclonal antibody was purified using a proprietary chromatographic technique that includes covalently immobilizing the antigen proteins or peptides to agarose based beads. This purification method enhances specificity, reduces nonspecific binding of extraneous IgG and provides you with the most reliable reagent available for your early discovery research.
RRID
AB_2830856
Formulation
This antigen affinity purified polyclonal antibody has been 0.2 µm filtered and lyophilized from modified Dulbecco’s phosphate buffered saline (1X PBS) pH 7.2 – 7.3 containing 5.0% w/v trehalose with no calcium, magnesium, or preservatives present.
Antigen Distribution
IL-7Rα is expressed on bone marrow lymphoid precursors, pro-B cells, monocytes/macrophages, NK-cells, naïve T cells, memory CD4+ and CD8+ T cells, intestinal colorectal and renal carcinoma cell lines, and keratinocytes.
Endotoxin Level
< 0.1 EU/µg as determined by the LAL method
Immunogen
NS0-Derived Recombinant Mouse IL-7 Receptor α Extracellular Domain
Additional Information
Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change.
Keywords
Polyclonal Antibody, Interleukin-7 Receptor Alpha, IL7R, CD127, CDW127, IL-7 Rα, Mouse IL-7 Rα, Anti-Mouse IL-7 Rα, CD127 antigen, CD127, CD127ILRA, CDW127, IL-7 R alpha, IL-7 receptor subunit alpha, IL7R alpha, IL-7R subunit alpha, IL7R, IL7RA, IL-7Ra, IL-7R-alpha, interleukin 7 receptor alpha chain, interleukin 7 receptor isoform H5-6, interleukin 7 receptor, interleukin-7 receptor subunit alpha

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ug
Lieferbar: In stock
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