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Anti-Rat MAG - 25 µg

ArtNr LEIN-M1293-25ug
Hersteller Leinco Technologies
Menge 25 ug
Quantity options 100 ug 25 ug
Kategorie
Typ Antibody Primary
Applikationen WB, IHC
Specific against Rat (Rattus norvegicus)
Host Caprine
Citations 1. Ming, GL. et al. (2008) Molecular Brian 1: 10
2. Kelm, S. et al. (2001) FEBS Lett. 499: 262
3. Del Rio, JA. et al. (2005) Mol Cell Neurosci. 29: 471
4. Jay, DG. et al. (2003) J of Neurosci. 23: 3112
NCBI 29409
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Versandbedingung Raumtemperatur
Lieferbar
Manufacturer - Applications
IHC FFPE, WB
Manufacturer - Category
Polyclonal Antibodies>Growth Factors & Cytokines
Manufacturer - Targets
MAG
Country of Origin
USA
Shipping Temperature
Next Day Ambient
Storage Conditions
The lyophilized antigen affinity purified polyclonal antibody can be stored desiccated at -20°C to -70°C for twelve months from date of receipt. The reconstituted antibody can be stored for at least four weeks at 2-8°C. For long-term storage of the reconstituted antibody, aseptically aliquot into working volumes and store at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. No detectable loss of activity was observed after six months.
Product Description
Myelin-associated glycoprotein (MAG) is a transmembrane proteins that is a component of myelin in the central and peripheral nervous system.1 It promotes neurite outgrowth during the embryonic development, but inhibits axonal regeneration in the adult nervous system.2 MAG mediates cell-cell interactions between myelinating glial cells and neurons.3 MAG as an important component of the myelin-derived inhibition of nerve regeneration. The acute loss of MAG function can promote significant axon growth across a site of CNS nerve damage.4
Background
Myelin-associated glycoprotein (MAG) is a transmembrane proteins that is a component of myelin in the central and peripheral nervous system.1 It promotes neurite outgrowth during the embryonic development, but inhibits axonal regeneration in the adult nervous system.2 MAG mediates cell-cell interactions between myelinating glial cells and neurons.3 MAG as an important component of the myelin-derived inhibition of nerve regeneration. The acute loss of MAG function can promote significant axon growth across a site of CNS nerve damage.4
Other Applications Reported In Literature
IHC (NBF/Par.): This antibody should give satisfactory staining results when used at a concentration of 5 - 15 µg/ml. The recommended secondary antibody for IHC is PN:G505. For chromogenic detection with high signal and low background use PN:D100 or PN:K107.
PubMed
MAG
Manufacturer - Specificity
Goat Anti-Rat Myelin-Associated Glycoprotein (MAG) recognizes Rat MAG. This antigen affinity purified polyclonal antibody was purified using a proprietary chromatographic technique that includes covalently immobilizing the antigen proteins or peptides to agarose based beads. This purification method enhances specificity, reduces nonspecific binding of extraneous IgG and provides you with the most reliable reagent available for your early discovery research.
RRID
AB_2831288
Formulation
This antigen affinity purified polyclonal antibody has been 0.2 µm filtered and lyophilized from modified Dulbecco’s phosphate buffered saline (1X PBS) pH 7.2 – 7.3 containing 5.0% w/v trehalose with no calcium, magnesium, or preservatives present.
Endotoxin Level
< 0.1 EU/µg as determined by the LAL method
Immunogen
NS0 - Derived Recombinant Rat MAG
Additional Information
Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change.
Keywords
Polyclonal Antibody, MAG, Siglec-4a, GMA, Rat MAG, Anti-Rat MAG, GMAsialic acid binding Ig-like lectin 4A, MAG, myelin associated glycoprotein, myelin-associated glycoprotein, sialic acid-binding immunoglobulin-like lectin 4A, Siglec4a, Siglec-4a, S-MAG

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 25 ug
Lieferbar: In stock
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