Anti-Human Midkine - 100 µg

IHC FFPE, WB

Midkine

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Midkine (MK, MDK), or Neurite Growth-promoting Factor 2, is a basic heparin-binding growth factor1 , a member of the NEGF family founded by Pleiotrophin. It is a non-glycosylated protein. It is a developmentally important retinoic acid-responsive gene product strongly induced during mid-gestation, hence the name midkine. Restricted mainly to certain tissues in the normal adult, it is strongly induced during oncogenesis, inflammation and tissue repair. MK is capable of exerting activities such as cell proliferation, cell migration, angiogenesis and fibrinolysis. MK application could be a new therapeutic strategy for the treatment of ischemic heart failure.2

Immunohistochemistry: Suitable for use at concentration of 5-15 µg/mL.

Rabbit Anti-Human Midkine recognizes Human Midkine. This antigen affinity purified polyclonal antibody was purified using a proprietary chromatographic technique that includes covalently immobilizing the antigen proteins or peptides to agarose based beads. This purification method enhances specificity, reduces nonspecific binding of extraneous IgG and provides you with the most reliable reagent available for your early discovery research.

This antigen affinity purified polyclonal antibody has been 0.2 µm filtered and lyophilized from modified Dulbecco’s phosphate buffered saline (1X PBS) pH 7.2 – 7.3 containing 5.0% w/v trehalose with no calcium, magnesium, or preservatives present.

Purified Recombinant Human Midkine (> 98%)

Polyclonal Antibody, Midkine, MDK, FLJ27379, NEGF2 (Neurite Growth-Promoting Factor 2), MK, Human Midkine, Anti-Human Midkine, Amphiregulin-associated protein, ARAP, MDK, MEK, Midgestation and kidney protein, midkine neurite growth-promoting factor 2, Midkine, MK1, MKARAP, NEGF2, NEGF2FLJ27379, Neurite outgrowth-promoting factor 2, Neurite outgrowth-promoting protein