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Anti-Mouse NK1.1 [Clone PK136] — DyLight® 594 - 100 µg

Anti-Mouse NK1.1 [Clone PK136] — DyLight® 594 - 100 µg

ArtNr	LEIN-N222-100ug
Hersteller	Leinco Technologies
Menge	100 ug
Quantity options	100 ug 200 ug 50 ug
Kategorie	Antibodies Flow Cytometry Primary Antibodies
Typ	Antibody Monoclonal
Applikationen	FC
Clon	PK136
Specific against	Mouse (Murine, Mus musculus)
Host	Mouse
Citations	1. Koo, G. C. and Peppard, J. R. (1986) Hybridoma 3:301
NCBI	17059
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Versandbedingung	Gekühlt
Lieferbar
Manufacturer - Category	Primary Monoclonal Antibodies>Surfacetag Mouse CD Markers
Manufacturer - Targets	NK1.1
Country of Origin	USA
Shipping Temperature	Next Day 2 - 8°C
Storage Conditions	This DyLight® 594 conjugate is stable when stored at 2-8°C. Do not freeze.
Product Description	NK1.1 is a type II membrane protein that is part of the C-type lectin superfamily. NK1.1 contains a transmembrane domain and a cytoplasmic domain that are characteristic of C-type lectins. The function of NK cells is to mediate cytotoxicity and to secrete cytokines after immune stimulation. NK1.1 has been correlated with lysis of tumor cells In vitro and rejection of bone marrow allografts In vivo. It is also involved in NK cell activation, IFN-γ production, and cytotoxic granule release. NK-1.1 is commonly used as a mouse NK cell marker.
Background	NK1.1 is a type II membrane protein that is part of the C-type lectin superfamily. NK1.1 contains a transmembrane domain and a cytoplasmic domain that are characteristic of C-type lectins. The function of NK cells is to mediate cytotoxicity and to secrete cytokines after immune stimulation. NK1.1 has been correlated with lysis of tumor cells In vitro and rejection of bone marrow allografts In vivo. It is also involved in NK cell activation, IFN-γ production, and cytotoxic granule release. NK-1.1 is commonly used as a mouse NK cell marker.
PubMed	NK1.1
Excitation Laser	Red Laser (590 nm)
Manufacturer - Research Area	Immunology, Innate Immunity
Manufacturer - Specificity	Clone PK136 recognizes mouse NK1.1.
RRID	AB_2831451
Concentration	0.2 mg/ml
Formulation	This DyLight® 594 conjugate is formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.4, 1% BSA and 0.09% sodium azide as a preservative.
Antigen Distribution	NK-1.1 is encoded by the NKR-P1B/NKR-P1C gene and expressed on NK cells and NK-T cells in some mouse strains, including C57BL/6, FVB/N, and NZB, but not AKR, BALB/c, CBA/J, C3H, DBA/1, DBA/2, NOD, SJL, and 129.
Immunogen	Purified Recombinant Mouse Natural Killer Cells (> 98%)
Additional Information	Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change.
Keywords	Monoclonal Antibody, Natural Killer Cells, NK1.1, PK136, Mouse, Anti-Mouse Natural Killer Cells - DyLight® 594

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LEIN-N222-100ug-safety-datasheet.pdf