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Anti-Human Survivin (CT)

Anti-Human Survivin (CT)

ArtNr	LEIN-S485-0.5mg
Hersteller	Leinco Technologies
Menge	0.5 mg
Quantity options	0.1 mg 0.5 mg 1 mg 20 ug
Kategorie	Antibodies Primary Antibodies
Typ	Antibody Primary
Specific against	Human (Homo sapiens)
Host	Rabbit
Citations	1. Ambrosini, G. et al. (1997) Nat. Med. 3:917 2. Li, F. et al. (1998) Nature 396:580 3. Kobayashi, K. et al. (1999) Proc. Natl. Acad. Sci. USA 96:1457
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Versandbedingung	Raumtemperatur
Lieferbar
Manufacturer - Category	Primary Monoclonal Antibodies>Apoptosis & Cell Biology
Manufacturer - Targets	Survivin
Country of Origin	USA
Shipping Temperature	Next Day Ambient
Storage Conditions	This polyclonal antibody is stable for at least one week when stored at 2-8°C. For long term storage, aliquot in working volumes without diluting and store at –20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.
Product Description	Apoptosis, or programmed cell death, is related to many diseases, such as cancer. Apoptosis is triggered by a variety of stimuli including members in the TNF family and prevented by the inhibitor of apoptosis (IAP) proteins. IAP proteins form a conserved gene family that binds to and inhibits cell death proteases. A novel IAP protein was recently identified and designated survivin, apoptosis inhibitor 4 (API4), and TIAP.1-3 Survivin/TIAP interacted with the processed form of caspase-3 and inhibited its proteolytic activity. Survivin/TIAP is predominantly expressed in tissues of embryos, transformed cell lines, and many human cancers and lymphomas.1, 3
Background	Apoptosis, or programmed cell death, is related to many diseases, such as cancer. Apoptosis is triggered by a variety of stimuli including members in the TNF family and prevented by the inhibitor of apoptosis (IAP) proteins. IAP proteins form a conserved gene family that binds to and inhibits cell death proteases. A novel IAP protein was recently identified and designated survivin, apoptosis inhibitor 4 (API4), and TIAP.^1-3 Survivin/TIAP interacted with the processed form of caspase-3 and inhibited its proteolytic activity. Survivin/TIAP is predominantly expressed in tissues of embryos, transformed cell lines, and many human cancers and lymphomas.^{1, 3}
PubMed	Survivin
Manufacturer - Specificity	Rabbit Anti-Human Survivin recognizes an epitope near the C-terminus of Human Survivin. This polyclonal antibody was purified using affinity chromatography.
RRID	AB_2831755
Concentration	0.5 mg/ml
Formulation	This polyclonal antibody is formulated in phosphate buffered saline (PBS) pH 7.4 containing 0.02% sodium azide as a preservative.
Immunogen	PN:S492
Additional Information	Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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LEIN-S485-0.5mg-safety-datasheet.pdf