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Anti-Human Thyroid Stimulating Hormone Alpha - Purified

ArtNr LEIN-T103-1.0mg
Hersteller Leinco Technologies
Menge 1 mg
Kategorie
Typ Antibody Primary
Clon 176
Specific against Human (Homo sapiens)
Host Mouse
Citations 1. Matsumoto, K. et al. (1998) Analytical Sciences 14:421-3.
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Versandbedingung Gekühlt
Lieferbar
Manufacturer - Category
Primary Monoclonal Antibodies>Endocrinology Hormones
Manufacturer - Targets
Thyroid Stimulating Hormone Alpha
Country of Origin
USA
Shipping Temperature
Next Day 2-8°C
Storage Conditions
This Purified Antibody is stable when stored at 2-8°C. Do not freeze.
Product Description
Thyroid-stimulating hormone (TSH), also known as thyrotropin, is a glycoprotein hormone1 that regulates the endocrine function of the thyroid gland.2 The most important controller of TSH secretion is thyroid-releasing hormone. Thyroid-releasing hormone is secreted by hypothalamic neurons into hypothalamic-hypophyseal portal blood, finds its receptors on thyrotrophs in the anterior pituitary and stimulates secretion of TSH.1 Independent of age, thyroid cancer incidence correlates with higher TSH. Higher TSH is associated with extrathyroidal extension of disease.3
Background
Thyroid-stimulating hormone (TSH), also known as thyrotropin, is a glycoprotein hormone1 that regulates the endocrine function of the thyroid gland.2 The most important controller of TSH secretion is thyroid-releasing hormone. Thyroid-releasing hormone is secreted by hypothalamic neurons into hypothalamic-hypophyseal portal blood, finds its receptors on thyrotrophs in the anterior pituitary and stimulates secretion of TSH.1 Independent of age, thyroid cancer incidence correlates with higher TSH. Higher TSH is associated with extrathyroidal extension of disease.3
Cross Reactivity
Paired with Leinco Prod. No. T100, Clone No. 154: TSH 100%, BhCG < 1%, ihCG***%, LH < 1%, FSH < 1%.
Paired with Leinco Prod. No. T114, Clone No. 155: TSH 100%, BhCG < 1%, ihCG***%, LH < 1%, FSH < 1%.
*** inhibition of reaction
PubMed
Thyroid Stimulating Hormone Alpha
Manufacturer - Specificity
Mouse Anti-Human Thyroid Stimulating Hormone Alpha (TSH-α) (Clone 176) recognizes Human Thyroid Stimulating Hormone Alpha. This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
RRID
AB_2737563
Concentration
1.0 mg/ml
Formulation
This purified antibody is supplied in 0.05 M phosphate buffered saline (PBS), pH 7.4, containing 0.1% sodium azide.
Immunogen
Purified Recombinant Human TSH-α (> 98%)
Additional Information
Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 1 mg
Lieferbar: In stock
lieferbar

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