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Anti-Mouse γ/δ (TCR) [Clone UC7-13D5] — APC - 100 µg

ArtNr LEIN-T143-100ug
Hersteller Leinco Technologies
Menge 100 ug
Quantity options 100 ug 200 ug 50 ug
Kategorie
Typ Antibody Monoclonal
Applikationen FC
Clon UC7-13D5
Specific against Mouse (Murine, Mus musculus)
Host Hamster - Armenian
ECLASS 10.1 42030590
ECLASS 11.0 42030590
UNSPSC 12352203
Versandbedingung Raumtemperatur
Lieferbar
Manufacturer - Category
Mouse T-Cell Receptor Complex
Manufacturer - Targets
γ/δ T-Cell Receptor
Country of Origin
USA
Shipping Temperature
Next Day Ambient
Storage Conditions
This APC conjugate is stable when stored at 2-8°C. Do not freeze.
Product Description
The T cell receptor or TCR is a molecule found on the surface of T lymphocytes that is responsible for recognizing antigens bound to major histocompatibility complex (MHC) molecules. It is a heterodimer consisting of an α and β chain in 95% of T cells, while 5% of T cells have TCRs consisting of γ and δ chains. Engagement of the TCR with antigen and MHC results in activation of its T lymphocyte through a series of biochemical events mediated by associated enzymes, co-receptors and specialized accessory molecules.
Background
The T cell receptor or TCR is a molecule found on the surface of T lymphocytes that is responsible for recognizing antigens bound to major histocompatibility complex (MHC) molecules. It is a heterodimer consisting of an α and β chain in 95% of T cells, while 5% of T cells have TCRs consisting of γ and δ chains. Engagement of the TCR with antigen and MHC results in activation of its T lymphocyte through a series of biochemical events mediated by associated enzymes, co-receptors and specialized accessory molecules.
PubMed
γ/δ T-Cell Receptor
Excitation Laser
Red Laser (650 nm)
Manufacturer - Research Area
Adaptive Immunity, Immunology
Manufacturer - Specificity
The anti-mouse γ/δ T-cell receptor antibody reacts with all mouse TCR γ/δ heterodimers.
RRID
AB_2894346
Concentration
0.2 mg/ml
Formulation
This Allophycocyanin (APC) conjugate is formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.4, 1% BSA and 0.09% sodium azide as a preservative.
Antigen Distribution
γδ TCR expression is observed on a subset of cells in the thymus, intestinal epithelium, skin, liver, peripheral lymphoid tissues, and peritoneum. The γδ TCR is involved in the antigen recognition of some bacterial or tumor-associated antigens presented by MHC class I.
Additional Information
Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change.
Keywords
Monoclonal Antibody, γ/δ T-Cell Receptor, UC7-13D5, TCR, Mouse TCR, antibody, antibodies

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ug
Lieferbar: In stock
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