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Anti-Mouse Vγ2 TCR - FITC - 500 µg

ArtNr LEIN-T212-500ug
Hersteller Leinco Technologies
Menge 500 ug
Quantity options 500 ug 50 ug
Kategorie
Typ Antibody Monoclonal
Applikationen FC
Clon UC3-10A6
Specific against Mouse (Murine, Mus musculus)
Host Hamster - Armenian
ECLASS 10.1 42030590
ECLASS 11.0 42030590
UNSPSC 12352203
Versandbedingung Raumtemperatur
Lieferbar
Manufacturer - Applications
Quality Tested by Leinco Flow Cytometry: This antibody has been quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is ≤0.25 µg per million cells in 100 µl volume. Each lot of this antibody is quality control tested.
Manufacturer - Category
Mouse T-Cell Receptor Complex|Primary Monoclonal Antibodies
Manufacturer - Targets
Vγ 2 T-Cell Receptor
Country of Origin
USA
Shipping Temperature
Next Day Ambient
Storage Conditions
This FITC monoclonal antibody conjugate is stable when stored at 2-8°C. Do not freeze.
Product Description
The T cell receptor or TCR is a molecule found on the surface of T lymphocytes that is responsible for recognizing antigens bound to major histocompatibility complex (MHC) molecules. It is a heterodimer consisting of an α and β chain in 95% of T cells, while 5% of T cells have TCRs consisting of γ and δ chains. Engagement of the TCR with antigen and MHC results in activation of its T lymphocyte through a series of biochemical events mediated by associated enzymes, co-receptors and specialized accessory molecules.
Background
The T cell receptor or TCR is a molecule found on the surface of T lymphocytes that is responsible for recognizing antigens bound to major histocompatibility complex (MHC) molecules. It is a heterodimer consisting of an α and β chain in 95% of T cells, while 5% of T cells have TCRs consisting of γ and δ chains. Engagement of the TCR with antigen and MHC results in activation of its T lymphocyte through a series of biochemical events mediated by associated enzymes, co-receptors and specialized accessory molecules.
Function
Might play a role in a previously unrecognized form of immunological surveillance for stress-induced self-antigens.
PubMed
Vγ 2 T-Cell Receptor
Excitation Laser
Blue Laser (490 nm)
Manufacturer - Research Area
Adaptive Immunity, Immunology
Manufacturer - Specificity
This antibody reacts with Vγ 2 T-Cell Receptor (TCR)-bearing T lymphocytes.
RRID
AB_2892975
Concentration
0.2 mg/ml
Formulation
This Fluorescein (FITC) conjugate is formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.4, 1% BSA and 0.09% sodium azide as a preservative.
Product Preparation
The antibody was purified by protein a affinity chromatography, and conjugated with FITC under optimal conditions.
Antigen Distribution
Vγ 2 T-Cell Receptor (TCR)-bearing T lymphocytes make up a significant proportion of γδ TCR-bearing cells in the late fetal and adult thymus and adult peripheral lymphoid tissues and lung.
Immunogen
G8 mouse T cells
Additional Information
Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 500 ug
Lieferbar: In stock
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