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Anti-Mouse CD120a (TNFR1) [Clone 55R-170] – Purified - 50 µg

Anti-Mouse CD120a (TNFR1) [Clone 55R-170] – Purified - 50 µg

ArtNr	LEIN-T248-50ug
Hersteller	Leinco Technologies
Menge	50 ug
Quantity options	500 ug 50 ug
Kategorie	Antibodies Flow Cytometry Immunoprecipitation Primary Antibodies
Typ	Antibody Monoclonal
Applikationen	FC, IP
Clon	55R-170
Specific against	Mouse (Murine, Mus musculus)
Host	Hamster - Armenian
Citations	1. Dana, R. et al. (2000) Arch Ophthalmol. 118: 1666 2. Donner, DB. et al. (2008) J Immunol. 181: 1288 3. Pasparakis, M. et al. (2008) Nat Immunol. 9: 1015
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Versandbedingung	Raumtemperatur
Lieferbar
Manufacturer - Category	Primary Monoclonal Antibodies>Growth Factors and Cytokines
Manufacturer - Targets	TNFR1
Country of Origin	USA
Shipping Temperature	Next Day Ambient
Storage Conditions	This purified antibody is stable when stored at 2-8°C. Do not freeze.
Product Description	Tumor Necrosis Factor Receptor Type I (TNFRI) is a 55kD Type I transmembrane protein. TNFRI is expressed independently of TNFRII at low levels on a wide variety of cell types. TNFRI binds TNF-α and TNF-ß (also known as LT-α). The subsequent signaling is known to be important for inducing cytolytic activity, antiviral activity, expression of manganous superoxide dismutase and intercellular adhesion molecule (ICAM), IL-6 mRNA accumulation and NF-ĸB induction. TNFRI carries an approximately 80 amino acid death domain near its carboxy terminus capable of transmitting an apoptotic signal through its interaction with TRADD (TNF Receptor I associated death domain protein). Binding of 55R-170 antibody to TNFRI has been shown to block in vitro and in vivo receptor signaling initiated by ligand binding.
Background	Tumor Necrosis Factor Receptor Type I (TNFRI) is a 55kD Type I transmembrane protein. TNFRI is expressed independently of TNFRII at low levels on a wide variety of cell types. TNFRI binds TNF-α and TNF-ß (also known as LT-α). The subsequent signaling is known to be important for inducing cytolytic activity, antiviral activity, expression of manganous superoxide dismutase and intercellular adhesion molecule (ICAM), IL-6 mRNA accumulation and NF-ĸB induction. TNFRI carries an approximately 80 amino acid death domain near its carboxy terminus capable of transmitting an apoptotic signal through its interaction with TRADD (TNF Receptor I associated death domain protein). Binding of 55R-170 antibody to TNFRI has been shown to block in vitro and in vivo receptor signaling initiated by ligand binding.
PubMed	TNFR1
Manufacturer - Research Area	Immunology, Innate Immunity
Manufacturer - Specificity	Clone 55R-170 recognizes mouse CD120a.
RRID	AB_2831864
Concentration	0.5 mg/ml
Formulation	This purified antibody is formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.4, 1% BSA and 0.09% sodium azide as a preservative.
Antigen Distribution	CD120a is constitutively expressed in most tissues.
Additional Information	Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change.
Keywords	Monoclonal Antibody, TNFR1, CD120α, 55R-170, Mouse, Anti-Mouse TNFR1-Purified

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LEIN-T248-50ug-safety-datasheet.pdf