Anti-Human TrkC - 25 µg

B, CyTOF®, FC, IHC FFPE, WB

TrkC

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Tropomyosin-related kinase C (TrkC) is a receptor for neurotrophins, a family of closely related proteins that are important physiological regulators of the survival of specific neurons within the peripheral nervous system (PNS) of vertebrates.1 TrkC specifically mediates biological responses to neurotrophin-3.2

IHC (NBF/Par.): This antibody should give satisfactory staining results when used at a concentration of 15 µg/ml. The recommended secondary antibody for IHC is PN:G505. For chromogenic detection with high signal and low background use PN:D100 or PN:K107.
Blocking: Neutralization of receptor-ligand interaction - Approximately 1-3 μg/ml of thisantibody will block 50% of the binding of 5 ng/ml recombinant human NT-3 to immobilized recombinant human TrkC/Fc chimera (100 μl of a 1 μg/ml solution was coated in each well) in a functional ELISA assay.
CyTOF-ready: Ready to be labeled using established conjugation methods. No BSA or other carrier proteins that could interfere with conjugation.

Goat Anti-Human TrkC recognizes Human TrkC. This antigen affinity purified polyclonal antibody was purified using a proprietary chromatographic technique that includes covalently immobilizing the antigen proteins or peptides to agarose based beads. This purification method enhances specificity, reduces nonspecific binding of extraneous IgG and provides you with the most reliable reagent available for your early discovery research.

This antigen affinity purified polyclonal antibody has been 0.2 µm filtered and lyophilized from modified Dulbecco’s phosphate buffered saline (1X PBS) pH 7.2 – 7.3 containing 5.0% w/v trehalose with no calcium, magnesium, or preservatives present.

Purified Recombinant Human TrkC (> 98%)

Polyclonal Antibody, Tropomyosin-Related Kinase C, NTRK3, GP145, TrkC, Human TrkC, Anti-Human TrkC, EC 2.7.10, EC 2.7.10.1, ETS related protein-neurotrophic receptor tyrosine kinase fusion protein, ETV6-NTRK3 fusion, gp145trkC, GP145-TrkC, Neurotrophic tyrosine kinase receptor type 3, neurotrophic tyrosine kinase, receptor, type 3, NT 3 receptor, NT-3 growth factor receptor, NTRK3, TrkC tyrosine kinase, TrkC, trk-C, TRKCneurotrophin 3 receptor, tyrosine kinase receptor C