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Human IFN-beta 1/IFNB1 antibody

ArtNr NKM-ATGA0587-100ul
Hersteller NKMAX
Menge 100 ul
Quantity options 100 ul 50 ul
Kategorie
Typ Antibody Monoclonal
Format Liquid
Applikationen WB, ICC, ELISA
Clon AT4F8
Specific against Human (Homo sapiens)
Host Mouse
Isotype IgG1 Kappa
Konjugat/Tag Unconjugated
Citations Fierlbeck G, et al. (1992) Hautarzt. 43(1):16-21.
Panitch HS. (1992) Drugs. 44(6):946-62.
NCBI NP_002167
ECLASS 10.1 42030590
ECLASS 11.0 42030590
UNSPSC 12352203
Alias Ifb,IFN-beta,IFNB,Interferon beta 1,Interferon beta,Fibroblast interferon
Similar products IFN-b, ATGA0587-10ug, ATGA0587-20ug, ATGA0587-50ug, ATGA0587-100ug, ATGA0587-250ug, ATGA0587-500ug, ATGA0587-1mg, ATGA0587-10, ATGA0587-20, ATGA0587-50, ATGA0587-100, ATGA0587-250, ATGA0587-500, ATGA0587-1
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Manufacturer - Type
Antibodies
Manufacturer - Applications
ELISA, WB, ICC/IF
Manufacturer - Category
Monoclonal antibody
Storage Conditions
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Description
Interferon beta 1, also known as IFN-beta, is produced mainly by fibroblasts and some epithelial cell types. IFN-beta is involved in the regulation of unspecific humoral immune responses and immune responses against viral infections. It also increases the expression of HLA class I antigens and blocks the expression of HLA class II antigens stimulated by IFN-gamma. Interferon beta 1 can be used for topic treatment of condylomata acuminata. Some studies suggest that Interferon beta 1 tends to prevent disease activity in patients with multiple sclerosis
Concentration
1mg/ml (determined by BCA assay)
Formulation
Liquid in. Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% glycerol
Immunogen
Recombinant human IFN-beta (22-187aa) purified from E. coli
Ab Usage
The antibody has been tested by ELISA, Western blot and ICC/IF analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results.
Antigen Species
Human
Clonality
Monoclonal
Ab Purification Comment
By protein-A affinity chromatography
Gene Category
Cancer
Manufacturer - Search Terms
IFN-b, ATGA0587-10ug, ATGA0587-20ug, ATGA0587-50ug, ATGA0587-100ug, ATGA0587-250ug, ATGA0587-500ug, ATGA0587-1mg, ATGA0587-10, ATGA0587-20, ATGA0587-50, ATGA0587-100, ATGA0587-250, ATGA0587-500, ATGA0587-1
IF Comment
ICC/IF analysis of IFN-beta in Hela cells. The cell was stained with ATGA0587 (1:100). The secondary antibody (green) was used Alexa Fluor 488. DAPI was stained the cell nucleus (blue).
WB Comment
The cell lysates (40ug) were resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human IFN-beta antibody (1:1000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system.
Lane 1.: HepG2 cell lysate
Lane 2.: HeLa cell lysate
Lane 3.: Jurkat cell lysate

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ul
Lieferbar: In stock
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