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STAT1 alpha Antibody

ArtNr PRS-1021-0.1mg
Hersteller ProSci
Menge 0.1 mg
Quantity options 0.02 mg 0.1 mg
Kategorie
Typ Antibody Polyclonal
Format Liquid
Applikationen WB, IF, IP, ICC, ELISA, IHC-P
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host Rabbit
Isotype IgG
Konjugat/Tag Unconjugated
Citations Leonard and O'Shea. Annu. Rev. Immunol. 1998; 16:293-322.
Schindler and Darnell. Annu. Rev. Biochem. 1995; 64:621-51.
Darnell. Science 1997; 277:1630-5.
Schindler et al. Proc. Natl. Acad. Sci. USA 1992; 89:7836-9.
NCBI STAT1
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias STAT1 alpha Antibody: CANDF7, ISGF-3, STAT91
Lieferbar
Manufacturer - Applications
WB: 0.5-1 μg/mL; IF: 20 μg/mL; IHC: 2.5 μg/mL; ICC: 10 μg/mL .

Antibody validated: Western Blot in human, mouse and rat samples; Immunofluorescence, Immunohistochemistry and Immunocytochemistry in human samples. All other applications and species not yet tested.
Shipping Temperature
blue ice or room temperature
Storage Conditions
STAT1 alpha antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Molecular Weight
Predicted: 87kD
Observed: 87 kD
Manufacturer - Research Area
Signal Transduction
Background
STAT1 alpha Antibody: STATs (signal transducers and activators of transcription) are a family of cytoplasmic latent transcription factors that are activated to regulate gene expression in response to a large number of extracellular signaling polypeptides including cytokines, interferons, and growth factors. After phosphorylation by JAK tyrosine kinases, STATs enter the nucleus to regulate transcription of many different genes. Among the seven STATs (Stat1, Stat2, Stat3, Stat4, Stat5a, Stat5b, and Stat6), Stat1, Stat3, Stat5a, and Stat5b have a wide activation profile. STAT1 is activated by many different ligands including IFN family (IFN-α , IFN-β , IFN-γ and IL-10), gp130 family (IL-6, IL-11, LIF, CNTF, and G-CSF), and receptor tyrosine kinases (EGF, PDGF, and CSF-1).
Protein Gi #
6274552
Purification
STAT1 alpha Antibody is Antibody is DEAE purified.
Isoforms
Human STAT1 alpha has two isoforms, including isoform 1 (750aa, 87.3kD) and isoform 2 (712aa, 83kD). Mouse STAT1 alpha has one isoform (749aa, 87.2kD) and Rat STAT1 alpha also has one isoform (749aa, 87.2kD). 1021 can detect longer human isoform, mouse and rat, but it cannot detect the shorter human isoform.
Positive Control 1
Positive Control 2
Positive Control 3
Positive Control 4
Positive Control 5
Concentration
1 mg/ml
Buffer
STAT1 alpha Antibody is supplied in PBS containing 0.02% sodium azide.
Homology
Predicted species reactivity based on immunogen sequence: Pig: (94%)
Immunogen
Anti-STAT1 alpha antibody (1021) was raised against a peptide corresponding to 38 amino acids near the carboxy terminus of human STAT1 alpha.

The immunogen is located within the last 50 amino acids of STAT1 alpha.
Clonality
Polyclonal
NCBI Official Name
signal transducer and activator of transcription 1, 91kDa
NCBI Organism
Homo sapiens
Disclaimer
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 0.1 mg
Lieferbar: In stock
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