IL-1RAcP Antibody

Blue Ice

Predicted: 63 kDa
Observed: 63 kDa

IL-1RAcP Antibody: The pro-inflammatory cytokine IL-1 induced cellular response requires two subunits of its receptor, IL-1 receptor I(IL-1RI) and IL-1 receptor accessory protein (IL-1RAcP). IL-1 RAcP forms a complex with IL-1RI in response to IL-1 treatment. The IL-1 receptor-associated kinase (IRAK), which mediates activation of NF-κ B inducing kinae (NIK) and of NF-κ B, recruites to the IL-1R complex through IL-1 RAcP. IL-1 activation of stress-activated protein kinase and of acid sphingomyelinase also requires IL-1RAcP. Like IL-1RI, IL-1RAcP subunit is essential for IL-1 mediated cellular response. IL-1RAcP is expressed in many tissues.

Trial Size

2599126

PRS-1204-0.1mg

1 mg/mL

IL-1RAcP antibody can be used for detection of IL-1RAcP by Western blot 1 μ g/mL. Antibody can also be used for immunocytochemistry starting at 5 μ g/mL.
Antibody validated: Western Blot in human samples and Immunocytochemistry in human samples. All other applications and species not yet tested.

It has no cross activity to other member in the IL-1 receptor family.

Polyclonal

Homo sapiens

Optimal dilutions for each application to be determined by the researcher.