Bnip3L Antibody

Blue Ice

Predicted: 24 kDa
Observed: 36, 40 kDa

Bnip3L Antibody: Members in the Bcl-2 family are critical regulators of apoptosis by either inhibiting or promoting cell death. Bcl-2 homology 3 (BH3) domain is a potent death domain. BH3 domain containing pro-apoptotic proteins, including Bad, Bax, Bid, Bik, Hrk, Nip3, and Bim, form a growing subclass of the Bcl-2 family. A novel BH3 domain containing protein was recently identified and designated Bnip3L, Bnip3alpha, and Nix (for Nip3-like protein X). Bnip3L/Bnip3alpha/Nix is a homolog of the E1B 19K/Bcl-2 binding and pro-apoptotic protein Bnip3. Overexpression of Bnip3L induces apoptosis. Bnip3L interacts with and overcomes suppresses by Bcl-2 and Bcl-xL. Bnip3L is localized in mitochondria. The messenger RNA of Bnip3L is ubiquitously expressed in human tissues. Bnip3L and Bnip3 form a new subfamily of the pro-apoptotic mitochondrial proteins.

Trial Size

4138825

PRS-1204-0.1mg

PRS-10-401-4um

Bnip3L Antibody is supplied in PBS containing 0.02% sodium azide.

Predicted species reactivity based on immunogen sequence: Mouse: (100%), Bovine: (100%)

Bnip3L antibody was raised against a 16 amino acid peptide near the center of human Bnip3L.

The immunogen is located within amino acids 60 - 110 of Bnip3L.

BCL2/adenovirus E1B 19kDa interacting protein 3-like

Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.