Caspase-14 Antibody

Blue Ice

Predicted: 28 kDa
Observed: 27 kDa

Caspase-14 Antibody: Caspases are a family of cysteine proteases that can be divided into apoptotic and inflammatory caspase subfamilies. Unlike the apoptotic caspases, members of the inflammatory subfamily are generally not involved in cell death but are associated with the immune response to microbial pathogens. Members of this subfamily include caspase-1, -4, -5, and -12 and can activate proinflammatory cytokines such as IL-1b and IL-18. Caspase-14 is highly expressed in embryonic but not adult tissues. It is processed and activated by caspase 8 and caspase 10 in vitro, and by anti-Fas agonist antibody or TNF-related apoptosis inducing ligand in vivo. The expression and processing of this caspase may be involved in the keratinocyte terminal differentiation, which is important for the formation of the skin barrier.

Trial Size

169666460

PRS-1205-0.1mg

PRS-10-201-4um

Caspase-14 Antibody is supplied in PBS containing 0.02% sodium azide.

Caspase-14 antibody was raised against a 16 amino acid synthetic peptide from near the carboxy terminus of human caspase-14.

The immunogen is located within the last 50 amino acids of Caspase-14.

caspase 14

Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.