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TLR2 Antibody

ArtNr PRS-3135-0.1mg
Hersteller ProSci
Menge 0.1 mg
Quantity options 0.02 mg 0.1 mg
Kategorie
Typ Antibody Polyclonal
Format Liquid
Applikationen WB, IF, ELISA, IHC-P
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host Rabbit
Isotype IgG
Konjugat/Tag Unconjugated
Citations Vogel SN, Fitzgerald KA, and Fenton MJ. TLRs: differential adapter utilization by toll-like receptors mediates TLR-specific patterns of gene expression. Mol. Interv. 2003; 3:466-77.
Takeda K, Kaisho T, and Akira S. Toll-like receptors. Annu. Rev. Immunol. 2003; 21:335-76.
Janeway CA Jr. and Medzhitov R. Innate immune recognition. Annu. Rev. Immunol. 2002; 20:197-216.
O'Neill LAJ, Fitzgerald FA, and Bowie AG. The Toll-IL-1 receptor adaptor family grows to five members. Trends in Imm. 2003; 24:286-9.
NCBI TLR2
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias TLR2 Antibody: TIL4,CD282,TIL4,Toll-like receptor 2
Versandbedingung Gekühlt
Lieferbar
Manufacturer - Type
Primary Antibodies
Shipping Temperature
Blue Ice
Storage Conditions
TLR2 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Manufacturer - Research Area
Innate Immunity
Background
TLR2 Antibody: Toll-like receptors (TLRs) are signaling molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. These proteins act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors such as Protein Kinase C (PKC) alpha/beta and NF-κ B. TLR2 can form heterodimers with either TLR1 or TLR6, and as a heterodimer can recognize a variety of bacterial and mycoplasma lipoproteins respectively.
By Type
Innate Immunity
Badges
Trial Size
Modifications
None
Protein Gi #
20140434
Purification
TLR2 Antibody is affinity chromatography purified via peptide column.
Positive Control 1
Positive Control 2
Positive Control 3
Concentration
1 mg/mL
Buffer
TLR2 Antibody is supplied in PBS containing 0.02% sodium azide.
Application Note
TLR2 antibody can be used for detection of TLR2 by Western blot at 1 μ g/mL. Despite its predicted molecular weight, TLR2 runs at ~100 kDa in SDS-PAGE. This polyclonal antibody can also detect TLR2 by immunohistochemistry at 2 μ g/mL. For immunofluorescence start at 10 μ g/mL.
Antibody validated: Western Blot in mouse samples; Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.
Immunogen
TLR2 antibody was raised against a peptide corresponding to 14 amino acids near the amino terminus of human TLR2.

The immunogen is located within the first 50 amino acids of TLR2.
Clonality
Polyclonal
NCBI Official Name
toll-like receptor 2
NCBI Organism
Homo sapiens
Disclaimer
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
User Note
Optimal dilutions for each application to be determined by the researcher.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 0.1 mg
Lieferbar: In stock
lieferbar

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