TIRP Antibody

Blue Ice

Predicted: 26 kDa
Observed: 27 kDa

TIRP Antibody: TIRP is a member of the Toll/interleukin-1 receptor (TIR) family, a group of proteins that include the Toll-like receptors (TLRs). TLRs are signaling molecules that recognize different pathogen-associated molecular patterns (PAMPs) and serve as an important link between the innate and adaptive immune responses. TIRP, along with other molecules such as TRIF, MAL, and MyD88, serves as an adaptor protein that allows for the interaction and activation of the IL-1R-associated kinase (IRAK) family, the subsequent activation of TNF receptor associated factor (TRAF)-6, and ultimately the activation of NF-κ B. Expression of TIRP appears to be essential for TLR4 signalling.

Trial Size

32435943

Cat. No. 1216 - PC-3 Cell Lysate

1 mg/mL

TIRP antibody can be used for detection of TIRP by Western blot at 1 μ g/mL. Antibody can also be used for immunocytochemistry starting at 10 μ g/mL. For immunofluorescence start at 10 μ g/mL.
Antibody validated: Western Blot in human samples; Immunocytochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.

TIRP antibody was raised against a peptide corresponding to 16 amino acids at the C-terminus of human TIRP.

The immunogen is located within the last 50 amino acids of TIRP.

toll-like receptor adaptor molecule 2

Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.