DRAM Antibody

ArtNr	PRS-33-062-100ug
Hersteller	ProSci
Menge	100 ug
Kategorie	Neuroscience Metabolism Glucose Homeostasis Cholesterol & Lipid Metabolism Molecular Targets for Neuroscience Neural Development Antibodies Obesity Western Blot Lipid & Fatty Acid Transport Primary Antibodies
Typ	Antibody Polyclonal
Format	Liquid
Applikationen	WB
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
Konjugat/Tag	Unconjugated
NCBI	DRAM
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	DRAM Antibody: DRAM,DRAM,DNA damage-regulated autophagy modulator protein 1,Damage-regulated autophagy modulator
Versandbedingung	Gekühlt
Lieferbar
Manufacturer - Type	Primary Antibodies
Shipping Temperature	Blue Ice
Storage Conditions	Aliquot and Store at -20˚ C. Avoid freez-thaw cycles.
Manufacturer - Research Area	Apoptosis, Autophagy, Cancer
Background	Autophagy is the mechanism by which lysosomes degrade unneeded or dysfunctional cellular components. p53 is a tumor suppressor protein that modulates autophagy and apoptosis. DRAM, or damage regulated autophagy modulator, is a lysosomal protein and effector of p53-mediated cell death. Many tumors show decreased DRAM expression and siRNA knockdown resulted in reduced cell death (Crighton et al, 2006).
By Type	Apoptosis, Autophagy, Cancer
Modifications	None
Purification	Protein A affinity chromatography
Concentration	0.5 mg/mL
Buffer	PBS with 0.1 mg/ml BSA and 0.05% sodium azide
Application Note	Western blot: 4-8 ug/ml Provided assay concentrations are suggestions only, antibody titration may be required for optimal results.
Immunogen	A recombinant protein fragment from the N-terminal region of human DRAM was used as the immunogen for this antibody.
Clonality	Polyclonal
NCBI Official Name	damage-regulated autophagy modulator
NCBI Organism	Homo sapiens
Disclaimer	Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
User Note	Optimal dilutions for each application to be determined by the researcher

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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Menge: 100 ug

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Lieferung vsl. bis 04.12.2025

Express-Lieferung: 23 Tage sparen

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