CTRP3 Antibody

Blue Ice

Predicted: 27kD
Observed: 30 kD (Post-modyfication: 1 N-linked glycosylation)

CTRP3 Antibody: Adipose tissue of an organism plays a major role in regulating physiologic and pathologic processes such as metabolism and immunity by producing and secreting a variety of bioactive molecules termed adipokines. One highly conserved family of adipokines is adiponectin/ACRP30 and its structural and functional paralogs, the C1q/tumor necrosis factor-alpha-related proteins (CTRPs) 1-7. Unlike adiponectin, which is expressed exclusively by differentiated adipocytes, the CTRPs are expressed in a wide variety of tissues. An analysis of the crystal structure of adiponectin revealed a structural and evolutionary link between TNF and C1q-containing proteins, suggesting that these proteins arose from a common ancestral innate immunity gene. It has been suggested that CTRP3 may play a role in skeletal development.

Trial Size

62739183

Human CTRP3 has 3 isoforms, including isoform 1 (246aa, 27kD), isoform 2 (198aa, 22kD) and isoform 3 (319aa, 35kD). Mouse CTRP3 has one isoform (246aa, 27kD) and Rat CTRP3 also has one isoform (319aa, 35kD). 3565 can detect human, mouse and rat.

PRS-1401-0.1mg

PRS-1205-0.1mg

1 mg/mL

WB: 1 μ g/mL; IHC: 2 μ g/mL; IF: 10 μ g/mL.
Antibody validated: Western Blot in human, mouse and rat samples; Immunohistochemistry in mouse samples; Immunofluorescence in mouse samples. All other applications and species not yet tested.

Anti-CTRP3 antibody (3565) was raised against a peptide corresponding to 16 amino acids near the center of human CTRP3.

The immunogen is located within amino acids 90-140 of CTRP3.

C1q and tumor necrosis factor related protein 3

Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.