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Apaf-1 Antibody [13F11]

Apaf-1 Antibody [13F11]

ArtNr	PRS-36-176-100ug
Hersteller	ProSci
Menge	100 ug
Kategorie	Antibodies Cell Biology Cell Status Apoptosis Immunoprecipitation Western Blot ELISA Immunocytochemistry Cardiovascular Research Ischemia & Reperfusion Injury Primary Antibodies
Typ	Antibody Primary
Format	Liquid
Applikationen	WB, IP, ICC, ELISA
Clon	13F11
Specific against	Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rat
Isotype	IgG2a Kappa
Konjugat/Tag	Unconjugated
NCBI	Apaf1
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Apoptosis Protease-activating Factor 1
Versandbedingung	Gekühlt
Lieferbar
Manufacturer - Type	Primary Antibodies
Shipping Temperature	Blue Ice
Storage Conditions	Stable for at least 1 year after receipt when stored at -20˚ C.
Manufacturer - Research Area	Apoptosis, Cancer
Background	Apaf-1 is a cytoplasmic protein that forms one of the central hubs in the apoptosis regulatory network. It contains (from the N terminal) a caspase recruitment domain (CARD), an ATPase domain (NB-ARC), few short helical domains and then several copies of the WD40 repeat domain. Upon binding cytochrome c and dATP, this protein forms an oligomeric apoptosome, mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis.
By Type	Apoptosis, Cancer
Modifications	None
Protein Gi #	Q9EPV5
Purification	>95% (SDS-PAGE)
Concentration	1 mg/ml
Buffer	Liquid. In PBS containing 0.02% sodium azide.
Application Note	Immunoprecipitation: (1:1000-1:2000) . Western Blot: (1:1000-1:2000) . Optimal conditions must be determined individually for each application.
Manufacturer - Specificity	Recognizes the CARD domain of mouse and rat Apaf-1. Does not cross-react with human Apaf-1.
Immunogen	Recombinant mouse Apaf-1 (aa 1-97) containing the N-terminal CARD domain.
Clonality	Monoclonal
NCBI Official Name	apoptotic peptidase activating factor 1
NCBI Organism	Rattus norvegicus
Disclaimer	Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
User Note	Optimal dilutions for each application to be determined by the researcher.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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Menge: 100 ug

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Lieferung vsl. bis 01.01.2026

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