TL1A Antibody

ArtNr	PRS-3789-0.1mg
Hersteller	ProSci
Menge	0.1 mg
Quantity options	0.02 mg 0.1 mg
Kategorie	Oncology Antibodies Cell Biology Cell Status Apoptosis Western Blot ELISA Primary Antibodies By Organ Lung Cancer Colorectal Cancer
Typ	Antibody Polyclonal
Format	Liquid
Applikationen	WB, ELISA
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus)
Host	Rabbit
Isotype	IgG
Konjugat/Tag	Unconjugated
Citations	Chinnayan AM, O'Rourke K, Yu GL, et al. Signal transduction by DR3, a death domain-containing receptor related to TNFR-1 and CD95. Science 1996; 274:990-2. Kitson J, Raven T, Jiang YP, et al. A death-domain-containing receptor that mediates apoptosis. Nature 1996; 384:372-5. Screaton GR, Xu XN, Olsen AL, et al. LARD: a new lymphoid-specific death domain containing receptor regulated by pre-mRNA splicing. Proc. Natl. Acad. Sci. USA 1997; 94:4615-9. Bodmer JL, Burns K, Schneider P. TRAMP, a novel apoptosis-mediating receptor with sequence homology to tumor necrosis factor receptor 1 and Fas (Apo-1/CD95). Immunity 1997; 6:79-88.
NCBI	TNFSF15
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	TL1A Antibody: TL1,TL1A,VEGI,VEGI192A,TL1,Tumor necrosis factor ligand superfamily member 15,TNF ligand-related molecule 1
Versandbedingung	Gekühlt
Lieferbar
Manufacturer - Type	Primary Antibodies
Shipping Temperature	Blue Ice
Storage Conditions	TL1A antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Molecular Weight	Predicted: 28 kDa Observed: 30 kDa
Manufacturer - Research Area	Apoptosis
Background	TL1A Antibody: Members in the TNF and its receptor superfamilies regulate immune responses and induce apoptosis. DR3 (also termed Wsl-1, Apo-3, TRAMP, and LARD) is preferentially expressed by T lymphocytes and upregulated during T cell activation. The ligand for DR3 was recently identified and designated TL1A. TL1A also binds decoy receptor DcR3/TR6, which is expressed in several lung and colon carcinomas and in some normal tissues. TL1A induces apoptosis and NF-κ B activation in DR3 expressing cells, which is antagonized by DcR3. TL1A is upregulated by proinflammatory cytokines TNF and IL-1. TL1A is a longer variant of TL1 (also called VEGI).
By Type	Apoptosis
Badges	Trial Size
Modifications	None
Protein Gi #	21745392
Purification	TL1A Antibody is Protein A purified.
Positive Control 1	PRS-1309-0.1mg
Concentration	1 mg/mL
Buffer	TL1A Antibody is supplied in PBS containing 0.02% sodium azide.
Application Note	TL1A antibody can be used for detection of TL1A by Western blot at 2 μ g/mL. Antibody validated: Western Blot in human samples. All other applications and species not yet tested.
Manufacturer - Specificity	TL1A will not cross-react with TL1.
Immunogen	TL1A antibody was raised against recombinant human TL1A.
Clonality	Polyclonal
NCBI Official Name	tumor necrosis factor (ligand) superfamily, member 15
NCBI Organism	Homo sapiens
Disclaimer	Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
User Note	Optimal dilutions for each application to be determined by the researcher.

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Menge: 0.1 mg

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