IL-21 Antibody

ArtNr	PRS-38-212-0.1mg
Hersteller	ProSci
Menge	0.1 mg
Kategorie	Antibodies Cell Biology Cell Culture Cytokines Western Blot ELISA Primary Antibodies
Typ	Antibody Primary
Format	Lyophilized
Applikationen	WB, ELISA
Specific against	Mouse (Murine, Mus musculus)
Host	Rabbit
Konjugat/Tag	Unconjugated
NCBI	Il21
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Interleukin-21IL-21
Versandbedingung	Raumtemperatur
Lieferbar
Manufacturer - Type	Primary Antibodies, Antibody Pairs
Shipping Temperature	Room Temp
Storage Conditions	IL-21 antibody is stable for at least 2 years from date of receipt at -20˚ C. The reconstituted antibody is stable for at least two weeks at 2-8˚ C. Frozen aliquots are stable for at least 6 months when stored at -20˚ C. Avoid repeated freeze-thaw cycles.
Manufacturer - Research Area	Immunology, Chemokines & Cytokines, Antibody Pairs
Background	A novel cytokine was recently identified in human and mouse and designated IL-21, which has significant homology to IL-2, IL-4, and IL-15. The receptor for IL-21 (IL-21R, also termed NILR for novel Interleukin receptor) is a new member of the class I cytokine receptor family. IL-21R forms a complex with the common cytokine receptor g chain, gc, and mediates IL-21 signaling. IL-21 and its receptor activate JAK-STAT signaling pathway. IL-21 is expressed in activated T cells, and HL-60 and THP-1 cell lines. IL-21 plays a role in the proliferation and maturation of NK, B and T cell populations.
By Type	Immunology, Chemokines & Cytokines
Modifications	None
Protein Gi #	55976590
Concentration	batch dependent
Application Note	ELISA: Indirect: To detect mIL-21 by indirect ELISA (using 100 μ L/well antibody solution) a concentration of 0.5 - 2.0 μ g/mL of this antibody is required. This antigen affinity purified antibody, in conjunction with compatible secondary reagents, allows the detection of at least 0.2 - 0.4 ng/well of recombinant mIL-21. Sandwich To detect mIL-21 by sandwich ELISA (using 100 μ L/well antibody solution) a concentration of 0.5 - 2.0 μ g/mL of this antibody is required. This antigen affinity purified antibody, in conjunction with our biotinylated Anti-Murine IL-21 as a detection antibody, allows the detection of at least 0.2 - 0.4 ng/well of recombinant mIL-21. Western Blot: To detect mIL-21 by Western Blot analysis this antibody can be used at a concentration of 0.1 - 0.2 μ g/mL. Used in conjunction with compatible secondary reagents the detection limit for recombinant mIL-21 is 1.5 - 3.0 ng/lane, under either reducing or non-reducing conditions.
Immunogen	Produced from sera of rabbits pre-immunized with highly pure (>98%) recombinant mIL-21 (Murine Interleukin-21). Murine IL-21 specific antibody was purified by affinity chromatography employing immobilized mIL-21 matrix.
Clonality	Polyclonal
NCBI Official Name	interleukin 21
NCBI Organism	Mus musculus
Disclaimer	This product is for research use only.
User Note	Centrifuge vial prior to opening.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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Menge: 0.1 mg

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