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MLH1 Antibody

ArtNr PRS-55-988-400ul
Hersteller ProSci
Menge 400 ul
Kategorie
Typ Antibody Polyclonal
Format Liquid
Applikationen WB, FC
Specific against Human (Homo sapiens)
Host Rabbit
Konjugat/Tag Unconjugated
Citations Ling, Z.Q., et al. Cancer Lett. 297(2):244-251(2010)
Qi, Y., et al. J. Biol. Chem. 285(43):33010-33017(2010)
Borras, E., et al. Cancer Res. 70(19):7379-7391(2010)
Mangoni, M., et al. Int. J. Radiat. Oncol. Biol. Phys. (2010) In press :
NCBI MLH1
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias DNA mismatch repair protein Mlh1,MutL protein homolog 1,MLH1,COCA2
Versandbedingung Gekühlt
Lieferbar
Manufacturer - Type
Primary Antibodies
Manufacturer - Isotype
Rabbit Ig
Shipping Temperature
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Molecular Weight
85 kDa
Manufacturer - Research Area
Cancer
Background
This gene was identified as a locus frequently mutated in
hereditary nonpolyposis colon cancer (HNPCC). It is a human homolog
of the E. coli DNA mismatch repair gene mutL, consistent with the
characteristic alterations in microsatellite sequences
(RER+phenotype) found in HNPCC. Alternative splicing results in
multiple transcript variants encoding distinct isoforms. Additional
transcript variants have been described, but their full-length
natures have not been determined.
By Type
Cancer
Modifications
None
Protein Gi #
730028
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Application Note
For WB starting dilution is: 1:1000
For FACS starting dilution is: 1:10~50
Immunogen
This MLH1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 452-480 amino acids from the Central region of human MLH1.
Clonality
Polyclonal
NCBI Official Name
DNA mismatch repair protein Mlh1
NCBI Organism
Homo sapiens
Disclaimer
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
User Note
Optimal dilutions for each application to be determined by the researcher.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 400 ul
Lieferbar: In stock
lieferbar

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