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MLH1 Antibody

MLH1 Antibody

Item no.	PRS-55-988-400ul
Manufacturer	ProSci
Amount	400 ul
Category	Oncology Antibodies By Cell Type Blastoma Carcinoma Glioma Hematology Leukemia Lymphoma Myeloma Melanoma Sarcoma Cell Biology Adenocarcinoma Cytoskeleton Flow Cytometry Western Blot Primary Antibodies By Organ Lung Cancer Colorectal Cancer small GTPases Ras Subfamily
Type	Antibody Polyclonal
Format	Liquid
Applications	WB, FC
Specific against	Human (Homo sapiens)
Host	Rabbit
Conjugate/Tag	Unconjugated
Citations	Ling, Z.Q., et al. Cancer Lett. 297(2):244-251(2010) Qi, Y., et al. J. Biol. Chem. 285(43):33010-33017(2010) Borras, E., et al. Cancer Res. 70(19):7379-7391(2010) Mangoni, M., et al. Int. J. Radiat. Oncol. Biol. Phys. (2010) In press :
NCBI	MLH1
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	DNA mismatch repair protein Mlh1,MutL protein homolog 1,MLH1,COCA2
Shipping Condition	Cool pack
Available
Manufacturer - Type	Primary Antibodies
Manufacturer - Isotype	Rabbit Ig
Shipping Temperature	Blue Ice
Storage Conditions	Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Molecular Weight	85 kDa
Manufacturer - Research Area	Cancer
Background	This gene was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). It is a human homolog of the E. coli DNA mismatch repair gene mutL, consistent with the characteristic alterations in microsatellite sequences (RER+phenotype) found in HNPCC. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described, but their full-length natures have not been determined.
By Type	Cancer
Modifications	None
Protein Gi #	730028
Purification	This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration	batch dependent
Buffer	Supplied in PBS with 0.09% (W/V) sodium azide.
Application Note	For WB starting dilution is: 1:1000 For FACS starting dilution is: 1:10~50
Immunogen	This MLH1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 452-480 amino acids from the Central region of human MLH1.
Clonality	Polyclonal
NCBI Official Name	DNA mismatch repair protein Mlh1
NCBI Organism	Homo sapiens
Disclaimer	Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
User Note	Optimal dilutions for each application to be determined by the researcher.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 400 ul

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Delivery expected until 11/6/2025

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