TRESK Antibody

Primary Antibodies

TRESK antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

TRESK Antibody: TRESK (TWIK-related spinal cord K+ channel) is a two-pore domain K+ channel that induces outward rectification and functions as a background K+ channel that is abundantly expressed in the spinal cord, thymus, spleen, and leukemic T-lymphocytes. TRESK is activated by increased cytoplasmic calcium concentration through calcineurin as well as by acetylcholine and histamine. It has been suggested that TRESK is linked to acute and chronic pain by activation of calcineurin. Other studies indicate that TRESK may play a role in the regulation of T-cell function and could be an excellent target to treat T-cell originated immune dysfunction.

Trial Size

32469495

PRS-1463-0.1mg

TRESK Antibody is supplied in PBS containing 0.02% sodium azide.

TRESK antibody was raised against a 17 amino acid synthetic peptide from near the center of human TRESK.

The immunogen is located within amino acids 210 - 260 of TRESK.

potassium channel, subfamily K, member 18

Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.