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TLR7 Antibody

ArtNr PRS-57-215-400ul
Hersteller ProSci
Menge 400 ul
Kategorie
Typ Antibody Polyclonal
Format Liquid
Applikationen WB
Specific against Human (Homo sapiens)
Host Rabbit
Konjugat/Tag Unconjugated
Citations Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Manuse, M.J., et al. Virology 405(2):383-389(2010)
Cros, J., et al. Immunity 33(3):375-386(2010)
Shen, N., et al. Proc. Natl. Acad. Sci. U.S.A. 107(36):15838-15843(2010)
NCBI TLR7
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias Toll-like receptor 7,TLR7
Versandbedingung Gekühlt
Lieferbar
Manufacturer - Type
Primary Antibodies
Manufacturer - Isotype
Rabbit Ig
Shipping Temperature
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Molecular Weight
121 kDa
Manufacturer - Research Area
Immunology, Signal Transduction
Background
The protein encoded by this gene is a member of the
Toll-like receptor (TLR) family which plays a fundamental role in
pathogen recognition and activation of innate immunity. TLRs are
highly conserved from Drosophila to humans and share structural and
functional similarities. They recognize pathogen-associated
molecular patterns (PAMPs) that are expressed on infectious agents,
and mediate the production of cytokines necessary for the
development of effective immunity. The various TLRs exhibit
different patterns of expression. This gene is predominantly
expressed in lung, placenta, and spleen, and lies in close
proximity to another family member, TLR8, on chromosome X.
By Type
Immunology, Signal Transduction
Modifications
None
Protein Gi #
20140876
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Application Note
For WB starting dilution is: 1:1000
Homology
Predicted species reactivity based on immunogen sequence: Mouse
Immunogen
This TLR7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 899-926 amino acids from the C-terminal region of human TLR7.
Clonality
Polyclonal
NCBI Official Name
Toll-like receptor 7
NCBI Organism
Homo sapiens
Disclaimer
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
User Note
Optimal dilutions for each application to be determined by the researcher.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 400 ul
Lieferbar: In stock
lieferbar

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