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TLR7 Antibody

TLR7 Antibody

Item no.	PRS-57-215-400ul
Manufacturer	ProSci
Amount	400 ul
Category	Oncology Neuroscience Neuroinflammation Aging & Neurological Disorders Antibodies By Cell Type Blastoma Cell Biology Western Blot Cell Stainings ECM Cardiovascular Research Atherosclerosis Primary Antibodies
Type	Antibody Polyclonal
Format	Liquid
Applications	WB
Specific against	Human (Homo sapiens)
Host	Rabbit
Conjugate/Tag	Unconjugated
Citations	Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010) Manuse, M.J., et al. Virology 405(2):383-389(2010) Cros, J., et al. Immunity 33(3):375-386(2010) Shen, N., et al. Proc. Natl. Acad. Sci. U.S.A. 107(36):15838-15843(2010)
NCBI	TLR7
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Toll-like receptor 7,TLR7
Shipping Condition	Cool pack
Available
Manufacturer - Type	Primary Antibodies
Manufacturer - Isotype	Rabbit Ig
Shipping Temperature	Blue Ice
Storage Conditions	Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Molecular Weight	121 kDa
Manufacturer - Research Area	Immunology, Signal Transduction
Background	The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is predominantly expressed in lung, placenta, and spleen, and lies in close proximity to another family member, TLR8, on chromosome X.
By Type	Immunology, Signal Transduction
Modifications	None
Protein Gi #	20140876
Purification	This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration	batch dependent
Buffer	Supplied in PBS with 0.09% (W/V) sodium azide.
Application Note	For WB starting dilution is: 1:1000
Homology	Predicted species reactivity based on immunogen sequence: Mouse
Immunogen	This TLR7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 899-926 amino acids from the C-terminal region of human TLR7.
Clonality	Polyclonal
NCBI Official Name	Toll-like receptor 7
NCBI Organism	Homo sapiens
Disclaimer	Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
User Note	Optimal dilutions for each application to be determined by the researcher.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 400 ul

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Delivery expected until 11/6/2025

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