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TNFRSF11B Antibody

ArtNr PRS-57-236-400ul
Hersteller ProSci
Menge 400 ul
Kategorie
Typ Antibody Polyclonal
Format Liquid
Applikationen WB, IF, IHC-P
Specific against Human (Homo sapiens)
Host Rabbit
Konjugat/Tag Unconjugated
Citations Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Liu, J.M., et al. J. Clin. Endocrinol. Metab. 95 (9), E112-E120 (2010) :
Lieb, W., et al. Arterioscler. Thromb. Vasc. Biol. 30(9):1849-1854(2010)
Paternoster, L., et al. J. Clin. Endocrinol. Metab. 95(8):3940-3948(2010)
NCBI TNFRSF11B
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias Tumor necrosis factor receptor superfamily member 11B,Osteoclastogenesis inhibitory factor,Osteoprotegerin,TNFRSF11B,OCIF,OPG
Versandbedingung Gekühlt
Lieferbar
Manufacturer - Type
Primary Antibodies
Manufacturer - Isotype
Rabbit Ig
Shipping Temperature
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Molecular Weight
46 kDa
Manufacturer - Research Area
Cell Cycle, Cell Cycle, Immunology, Obesity, Signal Transduction
Background
The protein encoded by this gene is a member of the
TNF-receptor superfamily. This protein is an osteoblast-secreted
decoy receptor that functions as a negative regulator of bone
resorption. This protein specifically binds to its ligand,
osteoprotegerin ligand, both of which are key extracellular
regulators of osteoclast development. Studies of the mouse
counterpart also suggest that this protein and its ligand play a
role in lymph-node organogenesis and vascular calcification.
Alternatively spliced transcript variants of this gene have been
reported, but their full length nature has not been determined.
By Type
Cell Cycle, Cell Cycle, Immunology, Obesity, Signal Transduction
Modifications
None
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Application Note
For WB starting dilution is: 1:1000
For IF starting dilution is: 1:10~50
For IHC-P starting dilution is: 1:10~50
Immunogen
This TNFRSF11B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 243-271 amino acids from the Central region of human TNFRSF11B.
Clonality
Polyclonal
NCBI Official Name
Tumor necrosis factor receptor superfamily member 11B
NCBI Organism
Homo sapiens
Disclaimer
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
User Note
Optimal dilutions for each application to be determined by the researcher.

Hinweis: Die dargestellten Informationen und Dokumente (Bedienungsanleitung, Produktdatenblatt, Sicherheitsdatenblatt und Analysezertifikat) entsprechen unserem letzten Update und sollten lediglich der Orientierung dienen. Wir übernehmen keine Garantie für die Aktualität. Für spezifische Anforderungen bitten wir Sie, uns eine Anfrage zu stellen.

Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 400 ul
Lieferbar: In stock
lieferbar

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