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TNFRSF11B Antibody

TNFRSF11B Antibody

Item no.	PRS-57-236-400ul
Manufacturer	ProSci
Amount	400 ul
Category	Neuroscience Neural Lineage Markers Antibodies Immunohistochemistry Western Blot Immunofluorescence Primary Antibodies
Type	Antibody Polyclonal
Format	Liquid
Applications	WB, IF, IHC-P
Specific against	Human (Homo sapiens)
Host	Rabbit
Conjugate/Tag	Unconjugated
Citations	Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010) Liu, J.M., et al. J. Clin. Endocrinol. Metab. 95 (9), E112-E120 (2010) : Lieb, W., et al. Arterioscler. Thromb. Vasc. Biol. 30(9):1849-1854(2010) Paternoster, L., et al. J. Clin. Endocrinol. Metab. 95(8):3940-3948(2010)
NCBI	TNFRSF11B
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	Tumor necrosis factor receptor superfamily member 11B,Osteoclastogenesis inhibitory factor,Osteoprotegerin,TNFRSF11B,OCIF,OPG
Shipping Condition	Cool pack
Available
Manufacturer - Type	Primary Antibodies
Manufacturer - Isotype	Rabbit Ig
Shipping Temperature	Blue Ice
Storage Conditions	Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Molecular Weight	46 kDa
Manufacturer - Research Area	Cell Cycle, Cell Cycle, Immunology, Obesity, Signal Transduction
Background	The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein is an osteoblast-secreted decoy receptor that functions as a negative regulator of bone resorption. This protein specifically binds to its ligand, osteoprotegerin ligand, both of which are key extracellular regulators of osteoclast development. Studies of the mouse counterpart also suggest that this protein and its ligand play a role in lymph-node organogenesis and vascular calcification. Alternatively spliced transcript variants of this gene have been reported, but their full length nature has not been determined.
By Type	Cell Cycle, Cell Cycle, Immunology, Obesity, Signal Transduction
Modifications	None
Purification	This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration	batch dependent
Buffer	Supplied in PBS with 0.09% (W/V) sodium azide.
Application Note	For WB starting dilution is: 1:1000 For IF starting dilution is: 1:10~50 For IHC-P starting dilution is: 1:10~50
Immunogen	This TNFRSF11B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 243-271 amino acids from the Central region of human TNFRSF11B.
Clonality	Polyclonal
NCBI Official Name	Tumor necrosis factor receptor superfamily member 11B
NCBI Organism	Homo sapiens
Disclaimer	Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
User Note	Optimal dilutions for each application to be determined by the researcher.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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Amount: 400 ul

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Delivery expected until 11/6/2025

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