CD97 Antibody

Primary Antibodies

Blue Ice

92 kDa

This gene is a member of the EGF-TM7 family of class II
seven-span transmembrane (7-TM) molecules, likely encoded by a gene
cluster on the short arm of chromosome 19. The encoded product is a
glycoprotein that is present on the surface of most activated
leukocytes and spans the membrane seven times, which is a defining
feature of G protein-coupled receptors. The protein has an extended
extracellular region with several N-terminal epidermal growth
factor (EGF)-like domains, which mediate binding to its cellular
ligand, decay accelerating factor (DAF, CD55), a regulatory protein
of the complement cascade. The presence of structural features
characteristic of extracellular matrix proteins and transmembrane
proteins suggests that this protein is a receptor involved in both
cell adhesion and signaling processes early after leukocyte
activation. Alternative splicing has been observed for this gene
and three variants have been found.

None

This antibody is purified through a protein A column, followed by peptide affinity purification.

Supplied in PBS with 0.09% (W/V) sodium azide.

This CD97 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 707-736 amino acids from the C-terminal region of human CD97.

CD97 antigen

Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.