CD97 Antibody

For WB starting dilution is: 1:1000

For IHC-P starting dilution is: 1:10~50

blue ice or room temperature

92 kDa

This gene is a member of the EGF-TM7 family of class IIseven-span transmembrane (7-TM) molecules, likely encoded by a genecluster on the short arm of chromosome 19. The encoded product is aglycoprotein that is present on the surface of most activatedleukocytes and spans the membrane seven times, which is a definingfeature of G protein-coupled receptors. The protein has an extendedextracellular region with several N-terminal epidermal growthfactor (EGF)-like domains, which mediate binding to its cellularligand, decay accelerating factor (DAF, CD55), a regulatory proteinof the complement cascade. The presence of structural featurescharacteristic of extracellular matrix proteins and transmembraneproteins suggests that this protein is a receptor involved in bothcell adhesion and signaling processes early after leukocyteactivation. Alternative splicing has been observed for this geneand three variants have been found.

This antibody is purified through a protein A column, followed by peptide affinity purification.

Supplied in PBS with 0.09% (W/V) sodium azide.

Polyclonal

Homo sapiens