RHOC Antibody

Primary Antibodies

Blue Ice

22 kDa

This gene encodes a member of the Rho family of small
GTPases, which cycle between inactive GDP-bound and active
GTP-bound states and function as molecular switches in signal
transduction cascades. Rho proteins promote reorganization of the
actin cytoskeleton and regulate cell shape, attachment, and
motility. The protein encoded by this gene is prenylated at its
C-terminus, and localizes to the cytoplasm and plasma membrane. It
is thought to be important in cell locomotion. Overexpression of
this gene is associated with tumor cell proliferation and
metastasis. Multiple alternatively spliced variants, encoding the
same protein, have been identified.

None

This antibody is purified through a protein A column, followed by peptide affinity purification.

Supplied in PBS with 0.09% (W/V) sodium azide.

Predicted species reactivity based on immunogen sequence: Bovine

Polyclonal

Homo sapiens

Optimal dilutions for each application to be determined by the researcher.